Choosing an Anti-Wrinkle Ingredient

Your mother wants to reduce existing smile lines and forehead wrinkles, which is different from preventing new wrinkles or solely focusing on collagen production.

• Acetyl Hexapeptide-8 (eq Argireline): This ingredient works by reducing muscle contractions that cause expression lines, especially on the forehead and around the eyes. It is suitable for skin that already has wrinkles.
• Pal-GHK, Pal-GQPR (eq Matrixyl 3000): This ingredient helps stimulate the synthesis of collagen and other important skin components, which helps firm the skin, reduce wrinkles, and increase elasticity. It is suitable for preventing and restoring overall skin youthfulness.

According to the staff's advice and the product information, if you want to focus on reducing existing wrinkles, ingredients that work similarly to Argireline are helpful.

Regarding Homeostatine™, DMAE Bitartrate, Pepha®-Tight, and Gladback, initial searches did not find direct product matches for these specific names in the database, so I cannot provide specific details on their efficacy and mechanism to compare them with Argireline or Matrixyl 3000 at this time.

Therefore, if you wish to choose only one ingredient that specifically targets existing wrinkles, based on the options you mentioned and the confirmed information, Acetyl Hexapeptide-8 (eq Argireline) would be the most suitable choice for reducing expression lines like smile lines and forehead wrinkles.

However, combining Acetyl Hexapeptide-8 with Matrixyl 3000 is often recommended because Argireline helps relax wrinkles caused by muscle movement, while Matrixyl 3000 helps strengthen the skin's structure from within, providing a more comprehensive result. But if you need to choose just one ingredient to focus on existing wrinkles, Argireline is the answer.