Comparison of Propylene Glycol Dicaprylate/Dicaprate and LipidSoft™ DS (Diisopropyl Sebacate)

Here's a comparison of Propylene Glycol dicaprylate/dicaprate and LipidSoft™ DS based on your questions:

1. Sunscreen Solubility: Both ingredients are effective solvents for UV filters and are commonly used in sunscreen formulations to help dissolve these active ingredients. LipidSoft™ DS is particularly noted for its ability to dissolve sunscreens well while providing a lightweight feel, which is often a challenge with other good sunscreen solvents.
2. Skin Feel: Both are described as lightweight emollient esters. They are known to provide a comfortable, non-greasy feel on the skin, making them suitable for various cosmetic applications, including sunscreens.
3. Clogging/Acne Risk: Neither Propylene Glycol dicaprylate/dicaprate nor LipidSoft™ DS is typically considered highly comedogenic. They are generally regarded as having a low risk of clogging pores or causing acne, although individual skin reactions can vary.
4. W/O Formulation with Low Water Content: Yes, both ingredients can be used in the oil phase of a Water-in-Oil (W/O) emulsion, even with a low water content like 5-10%. These esters are oil-soluble and contribute to the oil phase's properties, such as solvency for oil-soluble components and skin feel. The success and stability of such a W/O emulsion depend primarily on selecting an appropriate W/O emulsifier and optimizing the formulation process, rather than the suitability of these specific esters themselves, as they are compatible with the oil phase.