Compatibility and Application Method of Niacinamide and Vitamin C

Based on the forum discussion, when using Safe B3 (Niacinamide) and Vitamin C (specifically L-Ascorbic Acid, which is likely the form in "Vitamin C e feluric"), it is recommended to apply them at different times or wait at least 30 minutes between applications. This is because Vitamin B3 and Vitamin C can react with each other and cause degradation, reducing their effectiveness.

While some pre-formulated products might use stable Vitamin C derivatives or specific formulations to minimize interaction, when using individual ingredients or separate products, allowing time between applications is a good practice to ensure you get the full benefits of each ingredient.