Compatibility When Layering Serums

You're asking about which ingredients should not be used with Vitamin C E Ferulic serum, specifically mentioning Niacinamide (Safe-B3) and other anti-aging ingredients, when layering a moisturizing serum afterwards.

It's a common concern when using multiple active ingredients. The primary consideration when layering products, especially those with different pH levels like L-Ascorbic Acid (in Vitamin C E Ferulic) and Niacinamide, is potential irritation or reduced efficacy if applied immediately one after another.

However, as the staff reply indicated, waiting a sufficient amount of time between applying different serums is key. Allowing the first serum (Vitamin C E Ferulic) to fully absorb and the skin's pH to return closer to its normal level before applying the next serum significantly minimizes compatibility issues.

• Waiting Period: A waiting period of around 30 minutes, as suggested, is generally sufficient.
• Niacinamide (Safe-B3): While there were historical concerns about combining L-Ascorbic Acid and Niacinamide, modern, high-purity Niacinamide like Safe-B3 is much less likely to cause issues, especially when used with a waiting period between applications. You can typically use a moisturizing serum containing Niacinamide after waiting.
• Other Anti-Aging Ingredients: Many other anti-aging ingredients, such as peptides or retinoids, can also be incorporated into your routine. The same principle applies: allow the Vitamin C E Ferulic serum to absorb completely before applying a serum containing other anti-aging actives.

By giving each serum time to absorb and work, you can effectively use a variety of beneficial ingredients in your routine without significant compatibility problems.