Compatibility and pH for Mixing Azelaic Acid and Copper Peptide in Serum
คำถาม
I am formulating a cosmetic product and would like to know if Azelaic Acid (specifically `Liquid Azelaic™`) can be mixed with Copper Peptide. What are the compatibility considerations, especially regarding the required pH range for stability and efficacy? I am also aware from previous discussions that Copper Peptide can cause sensitivity in some individuals; are there any recommendations regarding this when formulating?
คำตอบ
Mixing Azelaic Acid and Copper Peptide
Yes, Azelaic Acid and Copper Peptide can be mixed in a cosmetic formulation. The key factor for successful mixing is ensuring the final pH of the product is within a range where both ingredients are stable.
- Azelaic Acid (specifically Liquid Azelaic™) is stable in formulations with a pH between 5 and 11.
- Copper Peptide is stable in formulations with a pH between 4.5 and 7.4.
Therefore, to maintain the stability and efficacy of both ingredients, the final formulation should have a pH carefully adjusted to be within the overlapping range of 5 to 7.4.
Combining these ingredients can offer synergistic benefits, with Azelaic Acid addressing issues like acne, oiliness, and hyperpigmentation, while Copper Peptide helps with skin regeneration, scar reduction, and anti-aging.
As noted in previous discussions, it is important to be aware that some individuals may experience sensitivity to Copper Peptide. It is recommended to perform a patch test before using a new formulation containing Copper Peptide and to start with a low concentration to assess skin tolerance.
