Combining Matrixyl 3000, Repair Activator, Galactomyces Ferment Filtrate, and Safe-B3

Yes, you can generally mix Matrixyl 3000, Repair Activator (Bifida Ferment Lysate), Galactomyces Ferment Filtrate (Pitera), and Safe-B3 (Vitamin B3/Niacinamide) together in a cosmetic formulation.

All four ingredients are water-soluble, which makes them compatible for combining in a water-based product like a serum or lotion.

Key Considerations for Mixing:

• Mixing Temperature: Matrixyl 3000, Repair Activator, and Galactomyces Ferment Filtrate are sensitive to heat. It is crucial to add these ingredients in the final phase of your formulation, after the main mixture has cooled down to below 40°C.
• pH Level: Safe-B3 (Niacinamide) is most stable and effective in a pH range of 4.0-7.0. Repair Activator has a pH range of 4-5.5, and Galactomyces Ferment Filtrate has a pH range of 4-7. These ranges are compatible. Ensure your final formulation's pH falls within the optimal range for Niacinamide (4.0-7.0) to maintain its efficacy and avoid potential irritation.

Regarding your specific concern about Vitamin B3 dissolving in Pitera: Since both Niacinamide (Vitamin B3) and Galactomyces Ferment Filtrate (Pitera) are water-soluble, Niacinamide powder will dissolve in a water-based solution containing Galactomyces Ferment Filtrate, provided there is enough water in the overall formulation.

In summary, these ingredients can be successfully combined in a water-based formula by adding them during the cooling phase and ensuring the final pH is within the recommended range.