Compatibility and Stability of Deoxyarbutin with Vitamin C
Question
Regarding the use of Deoxyarbutin with Vitamin C:
- Can Deoxyarbutin be used in the same formulation as Vitamin C? If so, which types of Vitamin C (e.g., L-Ascorbic Acid, Perfect-C, AA2G) are compatible, and what pH range is suitable?
- Does taking oral Vitamin C supplements affect the effectiveness or safety of topical Deoxyarbutin application?
Answer
Based on the information provided, whether deoxy arbutin can be used with Vitamin C depends primarily on the pH requirements of deoxy arbutin and the type of Vitamin C being used.
There are different types of Vitamin C, such as acidic L-Ascorbic Acid and more neutral forms like Perfect-C or AA2G. Compatibility depends on whether the optimal pH range for deoxy arbutin overlaps with the stable pH range for the chosen type of Vitamin C.
However, it's important to note that there are concerns regarding the stability of deoxy arbutin. Some research suggests it may not be stable in water and can break down into hydroquinone, which is a banned substance in many countries due to potential side effects. This is why some manufacturers may not use it.
To know for sure if deoxy arbutin is compatible with a specific type of Vitamin C, you would need to check the recommended pH range for deoxy arbutin with its manufacturer.
Regarding taking oral Vitamin C while applying deoxy arbutin topically, this is generally not expected to cause an interaction or affect the topical application. Oral intake has systemic effects, while topical application works on the skin surface.