Compatibility of Fat-Dissolving Gel Formula

Subject: Compatibility of Fat-Dissolving Gel Formula

Regarding the compatibility of your proposed gel formula for body application with the following ingredients:

• Chili Hot (Vanillyl Butyl Ether) 0.5%
• Menthol Water Soluble 2%
• Pro Polymer™ Silk (Polyquaternium-37) 1.5%
• Phenoxyethanol (Extra Pure) 1%
• Water 95%

Based on the ingredients listed:

• Physical Compatibility: The ingredients, including Pro Polymer™ Silk as a thickener and Phenoxyethanol as a preservative, are generally compatible with each other in a water-based gel system. You should be able to achieve a stable gel formulation.
• Sensory Compatibility: The main point to consider is the combination of Vanillyl Butyl Ether (warming agent) and Menthol (cooling agent). While these can sometimes be used together to create a complex sensation, they can also result in a conflicting feeling (simultaneously warm and cool) or one sensation dominating the other. The specific sensory outcome will depend on the concentrations and individual perception. It is highly recommended to test the formula on skin to evaluate the sensory experience.

In summary, the physical compatibility for forming a stable gel appears good. The primary consideration is the sensory interaction between the warming and cooling ingredients, which requires testing.