Compatibility of Gelling Agent (AnyGel) and Preservative (Eye Preserved) in Gel Formulation

Regarding your gel formulation for face application, the staff has reviewed the ingredients and noted a potential compatibility issue between AnyGel (Dehydroxanthan Gum) and Eye Preserved (Polyaminopropyl Biguanide).

• Potential Incompatibility: The staff has not tested the compatibility of AnyGel and Eye Preserved together and is unsure if they will cause issues.
• Recommended Test: If you wish to use Eye Preserved, the staff recommends performing a compatibility test first. Create the gel base by mixing AnyGel with water only. Do not add any other active ingredients yet. Then, add Eye Preserved to this gel base and observe for any immediate changes like clumping or thinning. If there are no issues after letting it sit for 6 hours, you can proceed to add the other ingredients.
• Alternative Preservative: The staff suggests using Mild Preserved Eco (Ethylhexylglycerin, Caprylyl Glycol) at 1% as an alternative preservative. It is known to be gentle and offers similar mildness to Eye Preserved at the same concentration. This alternative might avoid the potential compatibility issue.
• Mixing Method: Mixing by hand is possible, but ensure you mix thoroughly to ensure all ingredients, especially the gelling agent (AnyGel), are evenly dispersed and the gel forms properly without lumps.

In summary, the main point to consider is the compatibility between AnyGel and Eye Preserved. Please perform the recommended test or consider using the suggested alternative preservative.