Compatibility of Sym-White and EGT-Max in Formulation

Asked by: mititee On: May 11, 2021 Product Type: Cosmetics

Question

I would like to inquire if [url=http://www.myskinrecipes.com/shop/whitening-%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B9%83%E0%B8%AB%E0%B9%89%E0%B8%9C%E0%B8%B4%E0%B8%A7%E0%B8%82%E0%B8%B2%E0%B8%A7/898-sym-white-phenylethyl-resorcinol.html:2pt018un]Phenylethyl Resorcinol[/url:2pt018un] (eq. [url=http://www.myskinrecipes.com/shop/whitening-%E0%B8%AA%E0%B8%B2%E0%B8%AB%E0%B9%89%E0%B9%83%E0%B8%AB%E0%B9%89%E0%B8%9C%E0%B8%B4%E0%B8%A7%E0%B8%82%E0%B8%B2%E0%B8%A7/898-sym-white-phenylethyl-resorcinol.html:2pt018un]Sym-White™[/url:2pt018un]) and [url=https://www.myskinrecipes.com/shop/anti-wrinkle/8295-ergothioneine.html:2pt018un]EGT-Max™ (Ergothioneine 0.3%)[/url:2pt018un] can be formulated together?

  • Avoid ingredients in the [url=http://www.myskinrecipes.com/shop/%E0%B8%A1%E0%B8%AD%E0%B8%A2%E0%B8%8B%E0%B9%8C%E0%B9%80%E0%B8%88%E0%B8%AD%E0%B8%A3%E0%B9%8C/214-natural-moisturizing-amino-acids-%E0%B8%81%E0%B8%A3%E0%B8%94%E0%B8%AD%E0%B8%B0%E0%B8%A1%E0%B8%B4%E0%B9%82%E0%B8%99-%E0%B8%9A%E0%B8%B3%E0%B8%A3%E0%B8%B8%E0%B8%87%E0%B8%9C%E0%B8%B4%E0%B8%A7.html:2pt018un]Amino acids[/url:2pt018un], [url=http://www.myskinrecipes.com/shop/%E0%B8%A1%E0%B8%AD%E0%B8%A2%E0%B8%8B%E0%B9%8C%E0%B9%80%E0%B8%88%E0%B8%AD%E0%B8%A3%E0%B9%8C/149-urea-%E0%B8%A2%E0%B8%B9%E0%B9%80%E0%B8%A3%E0%B8%B5%E0%B8%A2-%E0%B8%84%E0%B8%A3%E0%B8%B5%E0%B8%A1.html:2pt018un]Urea[/url:2pt018un], or any protein group in the formula, as this may cause issues with [url=http://www.myskinrecipes.com/shop/whitening-%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B9%83%E0%B8%AB%E0%B9%89%E0%B8%9C%E0%B8%B4%E0%B8%A7%E0%B8%82%E0%B8%B2%E0%B8%A7/898-sym-white-phenylethyl-resorcinol.html:2pt018un]Sym-White[/url:2pt018un] (yellowing/separation). What about [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B8%81%E0%B8%B1%E0%B8%99%E0%B9%80%E0%B8%AA%E0%B8%B5%E0%B8%A2/1332-pentaerythrityl-tetra-di-t-butyl-hydroxyhydrocinnamate.html:2pt018un]Protec™ OX[/url:2pt018un] and [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B8%81%E0%B8%B1%E0%B8%99%E0%B9%80%E0%B8%AA%E0%B8%B5%E0%B8%A2/1392-ethylhexyl-methoxycrylene.html:2pt018un]Protec™ SQ[/url:2pt018un] in the formula?

Answer

Compatibility of Phenylethyl Resorcinol (Sym-White™) and EGT-Max™ (Ergothioneine)

Based on the information available, combining Phenylethyl Resorcinol (Sym-White™) and EGT-Max™ (Ergothioneine) in the same formulation is not recommended.

Here's why:

  • The product description for Phenylethyl Resorcinol explicitly states that you should avoid ingredients in the Amino Acids, Urea, or any protein group in the formula. These ingredients can cause problems such as yellowing or separation of the formulation when combined with Phenylethyl Resorcinol.
  • EGT-Max™ is described as a naturally occurring amino acid (Ergothioneine).

Therefore, due to EGT-Max™ being an amino acid, it is likely to cause the instability issues (yellowing/separation) with Phenylethyl Resorcinol that you are trying to avoid.

Regarding Protec™ OX and Protec™ SQ:

  • Protec™ OX is an antioxidant that helps protect ingredients from oxidation and free radicals.
  • Protec™ SQ is a singlet state quencher that helps protect ingredients from degradation caused by UV light.

Both Protec™ OX and Protec™ SQ are oil-soluble and are typically mixed into the oil phase of a formulation. They can provide valuable stability benefits to other ingredients in the formula. However, their inclusion does not resolve the fundamental incompatibility between Phenylethyl Resorcinol and EGT-Max™ due to the amino acid nature of EGT-Max™.

In summary, while Protec™ OX and Protec™ SQ can be useful stabilizers in a formulation containing an oil phase, you should avoid combining Phenylethyl Resorcinol and EGT-Max™ in the same product due to the potential for instability caused by EGT-Max™ being an amino acid.