Compatibility of Vitamin C (L-Ascorbic Acid), Retinal, and Plankton GP4G in Formulation

Asked by: samphan_tingthong On: September 06, 2018 Product Type: Cosmetics

Question

I would like to combine the following three ingredients in a single formulation:

  • Retinal (Retinaldehyde)
  • Plankton GP4G™
  • Vitamin C (L-Ascorbic Acid) ultra fine

Are these three ingredients compatible, or are there any issues when combining them?

Answer

Ingredient Compatibility: Vitamin C (L-Ascorbic Acid), Retinal, and Plankton GP4G

Regarding the compatibility of Vitamin C (L-ascorbic acid), Retinal (Retinaldehyde), and Plankton GP4G in a single formulation:

  • Retinal and Plankton GP4G: These two ingredients are generally compatible and can be included in the same formula without significant issues.

  • Vitamin C (L-Ascorbic Acid): L-ascorbic acid is a potent form of Vitamin C, but it is highly unstable, especially in the presence of water and at higher pH levels. It requires a low pH (typically around 3.5 or lower) to remain stable and effective.

Combining L-Ascorbic Acid with Retinal: This combination is challenging because Retinal, a form of Vitamin A, often requires a higher, less acidic pH range for optimal stability and efficacy compared to L-ascorbic acid. Formulating at the low pH required for L-ascorbic acid can destabilize Retinal or increase the risk of skin irritation. Conversely, formulating at a higher pH suitable for Retinal will quickly degrade L-ascorbic acid.

Therefore, while Retinal and Plankton GP4G can be combined, adding L-ascorbic acid to the same formula is difficult due to conflicting pH requirements and stability issues. It is generally recommended to use L-ascorbic acid and Retinal in separate products or at different times of the day to ensure you get the full benefits of each ingredient and minimize potential irritation.