Concentrated Hyaluronic Acid Serum Formulation for Device Use

Here is a suggested formulation for a concentrated Hyaluronic Acid serum suitable for use with a cosmetic device, applied weekly. This formulation uses the ingredients you mentioned:

• 4D Hyaluronic Acid (ID 6907): For a concentrated weekly treatment, you can use this at a higher percentage. The product description suggests up to 20% for very dry skin. For a potent serum, a range of 15-20% is suitable.
• Thickener (e.g., Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, ID 9589): This thickener is easy to use and works well in water-based gels. A usage rate of 1.5-2% should provide a good serum consistency.
• Preservative (e.g., Mild Preserved™ COS, ID 33939): While the 4D Hyaluronic Acid product itself contains a preservative (Phenoxyethanol), adding a broad-spectrum preservative like Mild Preserved™ COS at 1% helps ensure the stability and safety of the final formulation, especially since you are adding other components and water. Ensure the final pH is within the effective range of the preservative (pH 2-8 for Mild Preserved™ COS).
• Water: Use purified water to make up the remaining percentage.

Example Formulation (using 20% 4D Hyaluronic Acid):

• 4D Hyaluronic Acid: 20%
• Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer: 1.5%
• Mild Preserved™ COS: 1%
• Water: 77.5%

Mixing Instructions:

1. Disperse the Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer in the water and stir until a gel forms.
2. Add the 4D Hyaluronic Acid and stir until fully incorporated and homogenous.
3. Add the Mild Preserved™ COS and stir to combine.
4. Check and adjust the pH if necessary to be within the effective range of the preservative (pH 2-8).

This formulation provides a concentrated dose of Hyaluronic Acid for intensive weekly treatment. Remember to perform a small patch test before applying it to your entire face.