Cream Formulation with Multiple Brightening Actives: Compatibility and Potential for Irritation

Hello,

I have reviewed the formula you provided. As the previous staff member mentioned, this formula can be mixed.

Regarding the ingredients in this formula, it contains several key active ingredients focused on skin brightening at relatively high concentrations, including:

• Kojic Acid Dipalmitate 3%
• Vitamin B3 (Niacinamide) 4%
• NAG (N-Acetyl Glucosamine) 4%
• Activated Resorcinol S™ 5%
• Tranexamic Acid 3%

Using multiple active ingredients together at such high concentrations, especially Activated Resorcinol at 5% which is considered a very high concentration (typically used at much lower concentrations), may increase the chance of irritation, redness, peeling, or sensitization, particularly for individuals with sensitive skin.

However, the combination of Niacinamide and NAG is known to work synergistically to help reduce hyperpigmentation.

Other ingredients such as Allantoin, EDTA, Propylene Glycol, Glyceryl Stearate SE, Cetearyl Alcohol, Cyclomethicone, Butter Cream Maker™, and Phenoxyethanol SA are standard ingredients for a cream base and preservative, used at typical concentrations.

Recommendation:
Since this formula contains relatively high and diverse active ingredients, it is recommended to test the product on a small area of skin before applying it to the entire face to observe your skin's reaction. If irritation occurs, you should consider reducing the concentration of some active ingredients, especially Activated Resorcinol, or choose to use fewer active ingredients.