Dietary Supplement Capsule Formulation Questions
Asked by: chromos82
On: May 16, 2022
Product Type:
Food
Question
Regarding a dietary supplement capsule formulation containing specific vitamins and extracts, what is the recommended amount of Calcium dihydrogen phosphate, would its absence cause clumping and quality degradation, and are there any incompatibilities among the listed ingredients?
Answer
- Question 1: What is the recommended amount of Calcium dihydrogen phosphate?
Calcium dihydrogen phosphate is not listed in your provided formulation. It is commonly used in supplements as a filler, binder, or anti-caking agent, or as a source of calcium and phosphorus. There isn't a single "recommended dosage" for its use as a filler; the amount depends on the specific formulation needs. If used as a source of calcium or phosphorus, the recommended daily intake varies depending on age and sex, according to dietary guidelines. - Question 2: If Calcium dihydrogen phosphate is not included, will the extracts become moist and clump together, degrading quality?
Yes, potentially. If the ingredients in your formulation are prone to absorbing moisture from the air (hygroscopic), not including an anti-caking agent like Calcium dihydrogen phosphate could lead to the powder becoming moist, clumping together, and potentially reducing the stability and quality of the product over time. Anti-caking agents help prevent this by absorbing excess moisture or coating the particles to reduce their tendency to stick together. - Question 3: Which extracts and vitamins have conflicting effects and cannot be in the same formula?
Based on the ingredients listed in your formulation (Ascorbyl Palmitate, Glutathione, Coenzyme Q10, Alpha Lipoic Acid, Pine Bark Extract, Rice Extract (GABA), Chamomile Extract, Acai Berry Extract), there are no common known chemical incompatibilities that would cause them to significantly degrade or cancel each other out when formulated together in a capsule for oral consumption. Many of these ingredients, particularly the antioxidants (Vitamin C ester, Glutathione, Alpha Lipoic Acid, CoQ10, Pine Bark, Acai), are often combined and can work synergistically. GABA and Chamomile extract are also generally compatible with these ingredients in a formulation.
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