Dilution of Carbamide Peroxide 95% to 0.1% for Oral Care

Asked by: Anonymous On: August 29, 2025 Product Type: Cosmetics

Question

I have `carbamide peroxide 95%` and I want to use it in an oral care product. The regulatory requirement for the active carbamide peroxide in the final product is `0.1%`.

Could you please advise on the ratio of `glycerin` or `propylene glycol` needed to achieve this concentration?

Answer

To achieve a 0.1% concentration of active carbamide peroxide in your oral care product, using a 95% carbamide peroxide solution, you would need to mix it with glycerin or propylene glycol in the following approximate ratio:

  • Carbamide Peroxide 95% Solution: 1 part
  • Glycerin or Propylene Glycol: 949 parts

This means for every 1 gram of your 95% carbamide peroxide solution, you would add approximately 949 grams of glycerin or propylene glycol to reach the desired 0.1% active concentration.

Both glycerin and propylene glycol are commonly used as humectants and solvents in oral care formulations and are suitable for this purpose.