DMI, Penetration, Absorption Time, and Washing Off
Question
For a cream/lotion formulation containing DMI (Dimethyl Isosorbide) as a penetration enhancer, if I dislike the sticky texture after application and want to wash it off, how long should I wait at least to ensure that the active ingredients have been sufficiently absorbed so that washing will not affect the absorption?
Answer
Understanding DMI and Skin Absorption
DMI (Dimethyl Isosorbide) is a common ingredient used in cosmetic formulations as a penetration enhancer. Its primary function is to help other active ingredients in the product absorb into the skin more effectively and potentially faster.
Regarding your questions:
Can you wash off the cream/lotion?
Yes, you can wash off the product. However, washing it off too soon after application will likely remove the unabsorbed active ingredients and the DMI itself, which would reduce the overall effectiveness of the product. The active ingredients need time to penetrate the skin.How long should you wait before washing to ensure absorption?
There is no single, definitive answer to this, as the rate of absorption depends on several factors, including:- The specific active ingredients in the formulation.
- The concentration of DMI and other ingredients.
- The overall formulation base (cream, lotion, serum, etc.).
- Your individual skin type and condition.
While DMI helps speed up the process, complete absorption of all beneficial ingredients typically doesn't happen instantly. Waiting at least 15-30 minutes after application is a general guideline that allows a significant portion of the active ingredients to begin penetrating the skin. For best results, allowing the product to remain on the skin for several hours (e.g., applying at night) would maximize absorption.
If the sticky feeling is bothersome, consider applying a thinner layer of the product or using it during a time when the texture is less inconvenient, such as before bed.