Effect of PE-1 Aqua on Absorption of Oil-Soluble Ingredients in Layered Products

Based on the information provided, here is the answer regarding the use of PE1 Aqua with other layered products:

PE-1 Aqua, when included in a cream applied first, can help improve the absorption of subsequent layers.

However, PE-1 Aqua specifically enhances the absorption of water-soluble ingredients. It does not improve the absorption of oil-soluble ingredients.

Regarding your specific concerns:

• Vitamin C E Ferulic (Lite) serum: The staff reply indicates that PE-1 Aqua does not affect the absorption of oil-soluble components like Vitamin E. While the Vitamin C E Ferulic product contains Vitamin C, the staff's focus on Vitamin E (which is oil-soluble) and chemical sunscreens (also oil-soluble) suggests that PE-1 Aqua's effect is primarily on water-soluble substances. Therefore, PE-1 Aqua in the first cream should not prevent the absorption of the oil-soluble parts of your Vitamin C E Ferulic serum, such as Vitamin E.
• Chemical sunscreen: Chemical sunscreens are generally oil-soluble. Since PE-1 Aqua does not enhance the absorption of oil-soluble ingredients, there is no concern that it will cause excessive absorption of your chemical sunscreen.

The staff also mentioned that for oil-soluble active ingredients in subsequent formulas, if you want complete peace of mind about their full absorption, you could apply them at different times, perhaps 30-60 minutes apart. However, PE-1 Aqua's effect is not long-lasting.