Electrolyte-tolerant thickeners/bases for formulas with Azelaic Acid
คำถาม
Based on the issue where Azelaic Acid (which has high electrolyte levels) causes thinning and excessive foaming when using Pro Polymer (Acrylate Crosspolymer) or Pro Polymer Silk (Polyquaternium-37), what thickeners/bases are suitable for formulations (gel, cream, serum) that can tolerate or do not react with high electrolyte concentrations?
- For gel formulas, what alternatives to
Pro Polymerare recommended? - For cream formulas, what emulsifier/base is recommended?
- For serum formulas, what base is recommended?
คำตอบ
Based on the provided conversation:
The foaming is likely caused by the reaction between Azelaic Acid and either Pro Polymer (Acrylate Crosspolymer) or Pro Polymer Silk (Polyquaternium-37). The staff mentioned that Pro Polymer Silk is particularly sensitive to high electrolyte levels, which can occur with a high concentration of Azelaic Acid, leading to thinning and excessive foaming.
The conversation does not mention specific anti-foaming agents. Instead, it recommends using alternative thickeners that are more compatible with high electrolyte levels to prevent the foaming issue. The recommended alternatives depend on the type of formula:
- For gel formulas: Hydroxyethyl Cellulose or Xanthan Gum.
- For cream formulas: Butter Cream Maker.
- For serum formulas: Silky Serum Base.
ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง
Xanthan Gum (clear gel type, smooth texture)
Azelaic Acid (Liquid Azelaic™, e.q. Azeloglicina)
Pro Polymer™ (Gel Maker)
Silky Serum Base (Face/Eye)
Pro Polymer™ Silk
