Formula Compatibility and Mixing Procedure for Emulsion and Gel Bases

Question

Could you please analyze the compatibility and mixing procedure for the following three formulas?

Formula 1:
Water Phase:
Complex Salicylic Acid (Powder, Water-Soluble) 5%
Glycoprotein 2%
Collagen HP 3%
Adenosine Liposome 3%
Aloe Vera Extract 5%
Copper PCA 1%
Zinc PCA 1%
Dimethyl Isosorbide (DMI) 3%
Mild Preserved Eco 1%
น้ำกลั่น (Distilled Water) 34%
Oil Phase:
Phytosphingosine 2%
Alpha Lipoic Acid (ALA) (Powder) 1%
ActiveRelease Retinal 5%
ActiveProtec™ OX 1%
Tocotrienols 3%
Activated Resorcinol 2%
Resveratrol LongMax 3%
PalGLY (Palmitoyl Glycine) 1%
Perfect-C™ (Ascorbyl Tetraisopalmitate) 10%
Protec™ SQ 3%
Natural Bisabolol 1%
Ethyl Ferulate 1%
Light Lotion Maker 4%
LipidSoft™ Moist 5%

Formula 2:
Natural Moisturizing Amino Acids 5%
TreMoisture™ (Trehalose) 1%
Natural PHA (Gluconolactone) 2%
Urea 10%
Sodium Lactate (60% Liquid) 5%
Sodium PCA 50% 5%
Skin-mimic™ (Skin Barrier Restoration) 5%
GlucoBright™ (Acetyl glucosamine) 5%
Safe-B3™ (Vitamin B3, Niacinamide, Switzerland) 10%
Ethoxydiglycol 2%
Coenzyme Q10 (10%, Powder, Water-Soluble) 1%
Pal-GHK, Pal-GQPR (eq. Matrixyl 3000) 5%
Pep®-Coll (Palmitoyl Tripeptide-5) 5%
Acetyl Octapeptide-3 (eq. SNAP-8) 5%
Aloe Vera Gel (Lite) 34%

Formula 3:
Glycosaminoglycans Complex 2%
Ectoine (Ectoin, from Bio-fermentation) 2%
Plankton Artemia Extract 3%
Repair Activator™ Powder (Bifida Ferment Lysate) 1%
PiteraEx™ (Saccharomyces Lysate Extract) 2%
Madecassoside-80 (Centella Asiatica Extract) 1%
Pro-Cysteine 2%
Pisum Sativum Extract (Pea-Ex™) 5%
Marine Plankton (Lifting, Tightening) 2%
Japanese Cedar (Cryptomeria Japonica Bud Extract) 2%
beta glucan (Saccharomyces cerevisiae extract) 6%
Glutathione (L-Glutathione) (Extrasol, Japan) 2%
Lactobacillus Ferment Lysate 3%
Hydroxypropyl Tetrahydropyrantriol (eq. Pro-Xylane) 4%
MOIST72 5%
Superoxide Dismutase Liposome (SOD) 5%
Double Hyaluron Liquid 10%
Wrinkle-Fill™ (Acetyl L-Tyrosine) 2%
DMAE (SkinTight MD™) Liquid 5%
Calcium Pantothenate 3%
Aloe Vera Gel (Lite) 33%

Questions:

For Formula 1, can the water phase and oil phase be mixed separately and then combined directly?
For Formulas 2 and 3, can the ingredients be mixed directly into the Aloe Vera Gel (Lite) base?

MySkinRecipes Expert · Accepted Answer

Formula Analysis and Mixing Instructions

Formula 1 Mixing

For Formula 1, which is an emulsion containing both water-soluble and oil-soluble ingredients and uses Light Lotion Maker as the emulsifier, the correct mixing method is to prepare the water phase and the oil phase separately first. Once both phases are ready, you should gradually add the oil phase (containing the Light Lotion Maker) to the water phase while continuously mixing. This process is necessary to properly create a stable emulsion.

Formula 2 and 3 Mixing with Aloe Vera Gel (Lite)

For Formulas 2 and 3, which use Aloe Vera Gel (Lite) as the base, you can generally mix most ingredients directly into this base. The Aloe Vera Gel (Lite) is designed to be a base for adding various active ingredients.

However, it is important to note that the description for Aloe Vera Gel (Lite) lists certain incompatible substances. In Formula 3, the ingredient Double Hyaluron Liquid is specifically listed as incompatible with Aloe Vera Gel (Lite). Therefore, you cannot simply mix all ingredients in Formula 3 directly into the Aloe Vera Gel (Lite) base due to this incompatibility.

For Formula 2, based on the ingredients listed and the compatibility information for Aloe Vera Gel (Lite), the ingredients appear compatible and can likely be mixed directly into the base following the recommended mixing methods for adding powders and liquids to the gel base (stirring until dissolved/uniform).