Recommended Formula for Reducing Melasma, Freckles, Dark Spots, and Brightening Skin

Hello. I understand you want to mix ingredients to help reduce melasma, freckles, and dark spots and make your mother's facial skin brighter. You initially considered using Nano White 5%, Delentigo 5%, and an Aloe Vera gel base at 90%.

The initial formula you proposed might help with brightening to some extent, but if you specifically want to focus on reducing melasma, freckles, and dark spots, adding ingredients that are effective in directly inhibiting melanin production will help you see clearer and faster results.

Based on the suggestion you received, adding these ingredients is a very good idea:

• Vitamin B3 (Niacinamide): Helps reduce redness and dark spots, evens out skin tone, and strengthens the skin barrier.
• N-Acetyl Glucosamine: Works well with Vitamin B3 to reduce dark spots and gently exfoliates the skin, as well as helping to hydrate the skin. The combination of Niacinamide and N-Acetyl Glucosamine is known to be effective for hyperpigmentation.
• Alpha Arbutin: This substance inhibits the enzyme Tyrosinase, a key enzyme in melanin synthesis, which helps fade melasma, freckles, and dark spots and brightens the skin. It is considered an effective and safe ingredient.
• Tranexamic Acid: Has properties that help reduce melanin formation, especially suitable for melasma problems, particularly melasma caused by sun exposure.

In addition, there are other interesting and effective ingredients for reducing dark spots and brightening skin, such as ChromaWhite™ (Dimethylmethoxy Chromanyl Palmitate), which is a substance that significantly inhibits Tyrosinase and reduces melanin production.

Recommendations for a formula focused on reducing melasma, freckles, and dark spots:

You can use Aloe Vera gel as a base as desired and add active ingredients that specifically target dark spots. Consider using the ingredients mentioned above at their recommended usage rates to achieve the most effective formula.

Example formulation (adjust percentages based on suitability and recommended usage for each ingredient):

• Aloe Vera Gel (Base)
• Vitamin B3 (Niacinamide)
• N-Acetyl Glucosamine
• Alpha Arbutin
• Tranexamic Acid
• (May add) ChromaWhite™

Important Considerations:

• Reducing melasma, freckles, and dark spots requires time and consistency. Generally, you will start to see changes after continuous use for at least 1-2 skin cell turnover cycles (approximately 1-2 months), depending on individual skin condition and the severity of the problem.
• Sun protection is the most crucial factor in treating and preventing melasma, freckles, and dark spots from darkening. You should apply sunscreen with high SPF and PA+++ daily, even on cloudy days.

I hope this information is helpful in refining your formula.