Formulating a Light Essence for Dark Spots, Melasma, and Acne Marks: Compatibility, pH, and Mixing Order

Asked by: aoonjung On: December 22, 2020 Product Type: Cosmetics

Question

I would like to create a light essence formula to reduce shallow melasma, dark spots, and acne marks. I have drafted the following formula with percentages:

  1. Chamomile Water (Anthemis Nobilis) 69.40%
  2. Safe-B3™ (Vitamin B3, Niacinamide) 5.00%
  3. Hydro-White™ 1.50%
  4. 4MSK 3.00%
  5. Tranexamic Acid 3.00%
  6. 4D Hyaluronic Acid 5.00%
  7. French Pine Bark Extract 25 (Liquid) 2.50%
  8. Centella Asiatica Extract (Madecassoside) 0.50%
  9. GlucoBright™ (Acetyl glucosamine) 5.00%
  10. Japanese Cedar 1.00%
  11. PiteraEx™ 1.50%
  12. Ethoxydiglycol 2.60%

My questions are:

  1. Are the ingredients compatible?
  2. Safe-B3 has a pH of 6-7.5. Will this affect the formula?
  3. Can I mix ingredients 1-12 in order?

Answer

Analysis of Your Light Essence Formula

Here is an analysis of your proposed light essence formula for reducing shallow melasma, dark spots, and acne marks, addressing your specific questions:

1. Ingredient Compatibility

The ingredients you've selected are generally beneficial for addressing hyperpigmentation, dark spots, and improving skin texture. Many of them, such as Safe-B3 (Niacinamide), Hydro-White, 4MSK, Tranexamic Acid, GlucoBright, French Pine Bark Extract, Centella Asiatica Extract (Madecassoside), Japanese Cedar, and PiteraEx, are known for their brightening, anti-inflammatory, and skin-renewing properties.

However, there are a few points regarding compatibility and formulation stability:

  • Stability: Hydro-White and Tranexamic Acid are prone to discoloration and require a stabilizer like ActiveProtec™ OX (0.5-1.0%) for long-term stability. Your current formula does not include this.
  • Texture: 4MSK is an electrolyte and might affect the viscosity of the formula, potentially reducing the thickening effect of 4D Hyaluronic Acid.
  • Preservation: While Chamomile Water contains a preservative (phenoxyethanol 0.8%), the total percentage in the final formula (69.4%) might not be sufficient to preserve the entire product, especially given the high water content and presence of various botanical extracts. A broad-spectrum preservative system should be added to ensure microbial stability.

Functionally, the active ingredients complement each other well for the intended purpose.

2. Effect of Safe-B3 pH on the Formula

Safe-B3 (Niacinamide) has a pH range of 6-7.5, which is within its optimal working pH range (4.0-7.0) and acceptable range (3-8). The pH of individual ingredients contributes to the final pH of the formula. Many of the active ingredients in your formula work best in a slightly acidic to neutral pH range (e.g., Madecassoside 4-6.5, Japanese Cedar 3.5-6.5, GlucoBright 3-7, Safe-B3 4-7 optimal, Tranexamic Acid 3-8, 4D Hyaluronic Acid 3-9). The final pH of your mixed formula should be checked and ideally adjusted to be within the range of 5.0-6.5 to ensure optimal efficacy and stability of most ingredients while minimizing potential irritation.

So, the pH of Safe-B3 itself is not problematic, but you must ensure the final formula pH is suitable for all ingredients.

3. Mixing Order

The proposed mixing order (1-12) is not ideal due to the different solubility and heat sensitivity requirements of the ingredients. Hydro-White requires heating (60-80°C) to dissolve, while several other ingredients (4MSK, Madecassoside, PiteraEx) should avoid high heat or be added at lower temperatures.

A more appropriate mixing procedure would involve separating ingredients based on their properties:

  1. In a beaker, combine the water base (Chamomile Water) with ingredients that dissolve in water and can tolerate some heat, such as Ethoxydiglycol, Safe-B3, Tranexamic Acid, GlucoBright, Japanese Cedar, and French Pine Bark Extract. Stir to dissolve.
  2. Gently heat this mixture to 60-80°C to help dissolve Hydro-White. Add Hydro-White and stir until fully dissolved. Ensure the temperature does not exceed 60°C for prolonged periods after adding 4MSK.
  3. Remove from heat and let the mixture cool down to room temperature (below 40°C).
  4. Add 4D Hyaluronic Acid and stir until the desired gel texture is achieved.
  5. In a separate small container, dissolve or disperse the heat-sensitive ingredients like Centella Asiatica Extract (Madecassoside) and PiteraEx in a small amount of the cooled water base. Add this mixture to the main batch and stir well.
  6. Add your preservative system (in addition to the one in Chamomile Water) and ActiveProtec™ OX (highly recommended for stability).
  7. Check and adjust the final pH to 5.0-6.5.

This revised order ensures that ingredients requiring heat are dissolved properly, while heat-sensitive ingredients are added at a safe temperature.

In summary, your formula contains effective ingredients for your goals, but requires the addition of a stabilizer (ActiveProtec™ OX) and a comprehensive preservative system, along with careful attention to the mixing procedure and final pH adjustment for optimal performance and stability.