Information on Ingredients for Seborrheic Dermatitis and Hair Loss Shampoo

Hello! I understand you want to make a shampoo to treat seborrheic dermatitis, reduce hair loss, and itching, focusing on gentle and natural ingredients, and specifically want to use Zinc Pyrithione. Based on the information available, I have details on Zinc Pyrithione and Zinc PCA that might be helpful.

Zinc Pyrithione

(Product ID 7672)
This is a highly effective ingredient against fungi and bacteria, which are primary causes of dandruff and seborrheic dermatitis on the scalp.

• Usage in Shampoo: For rinse-off shampoos, Zinc Pyrithione can be used at a maximum concentration allowed by Thai and European FDA, which is 4% (equivalent to 2% active Zinc Pyrithione).
• Mixing Method: Zinc Pyrithione is insoluble in water and oil. It must be dispersed in the shampoo base by high-speed blending to ensure even distribution throughout the formula. The formula should have appropriate viscosity to prevent the powder from settling.
• Precautions:
  • Avoid using with Disodium EDTA or other Chelating Agents in the formula.
  • Incompatible with non-ionic surfactants.
  • Avoid using with Oxidants like Peroxides.

Zinc PCA

(Product ID 252)
This is another ingredient that helps reduce scalp oiliness, which can contribute to hair loss and dandruff/sebderm. It also helps reduce DHT production, a cause of oily scalp and hair loss.

• Usage in Shampoo: For shampoo or dandruff treatment, use at a rate of 0.2-0.3%.
• Mixing Method: Dissolve in the water phase. It is heat resistant but should not be heated for prolonged periods. The optimum pH is in the range of 3-7 (ideally 4-6).

Other Natural and Gentle Ingredients

To enhance the effectiveness in caring for the scalp and hair as you wish, you can consider adding natural ingredients with soothing, anti-inflammatory, or scalp-nourishing properties, such as Aloe Vera extract, Chamomile extract, or Tea Tree Oil (use with caution and diluted in a very small amount).

General Mixing Steps (when using a shampoo base)

If you have a shampoo base, adding these ingredients can be done by:

1. Prepare Zinc Pyrithione by dispersing it in a small amount of water or other compatible ingredients using a high-speed blender.
2. Prepare Zinc PCA by dissolving it in a small amount of water.
3. Gradually add the prepared ingredients (dispersed Zinc Pyrithione and dissolved Zinc PCA) into the shampoo base. Stir or blend until well combined. Ensure Zinc Pyrithione is evenly dispersed and does not settle.
4. Adjust the pH of the shampoo to be suitable for Zinc PCA (4-6) and for shampoo in general (usually around 5.5).
5. Other natural ingredients can be added at this stage, following the mixing instructions for each specific ingredient.

Limitation: I cannot provide a complete formula with percentages for all ingredients directly, but the information above should help you understand how to incorporate Zinc Pyrithione and Zinc PCA into your shampoo.

If you have further questions about specific ingredients or need information on other natural ingredients, feel free to ask.