Galactomyces Ferment Filtrate Formulation Questions

Here are the answers to your questions regarding using Galactomyces Ferment Filtrate in a 20% solution with DI water:

1. Preservation Requirement: Yes, a solution of 20% Galactomyces Ferment Filtrate in 80% DI water is a water-based formula and requires a preservative to prevent microbial contamination and ensure product stability and safety.
2. Does GFF contain preservatives? There are different types of Galactomyces Ferment Filtrate available. The standard type (like the one you linked, Galactomyces Ferment Filtrate (aka Pitera)) contains Butylene Glycol, which acts as a preservative. However, this may not provide sufficient broad-spectrum preservation on its own, especially in a dilute solution. There is also a Galactomyces Ferment Filtrate (Glycol Free, Glycerin Free, Preservative Free) version available which contains no added preservatives.
3. Effect of Preservatives on GFF: Galactomyces Ferment Filtrate is a filtrate containing beneficial metabolites, not live yeast cells. Standard cosmetic preservatives are designed to inhibit microbial growth and should not destroy the active components of the filtrate itself.
4. Compatibility with Probiotic Preservatives: Probiotic-type preservatives, such as Probio-Protect™ (Lactobacillus Ferment Preservative), are typically postbiotic ingredients derived from fermentation. They function as preservatives by producing antimicrobial substances. They are generally compatible with other fermented filtrates like Galactomyces Ferment Filtrate and are often preferred in formulations aiming for a "preservative-free" claim (as Lactobacillus Ferment is not classified as a traditional preservative).
5. Incompatible Ingredients: Based on the product information, Galactomyces Ferment Filtrate is stable within a pH range of 4-7. Avoid formulating with ingredients that would take the final product pH significantly outside this range. Also, avoid strong oxidizing or reducing agents which could potentially degrade the active components.