Formulation Adjustment for Anti-Aging Cream: Gelling Agent and Stability

ถามโดย: dvmapp เมื่อ: September 21, 2015 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I am developing an anti-aging, lifting, and brightening cream with the following ingredients:

  • Argireline
  • Matrixyl 3000
  • DMAE
  • Vitamin B3
  • N-Acetyl-D glucosamine
  • Centella Asiatica Extract
  • Light Cream Maker™
  • Phenoxyethanol
  • Water

I have a few questions regarding this formulation:

  1. Is Light Cream Maker™ suitable for this formula, especially when combined with ingredients like Centella Asiatica Extract and potentially high amounts of electrolytes like DMAE?
  2. Is Phenoxyethanol at 1% concentration suitable as a preservative for this formula? Are there any alternative preservatives that would be suitable?
  3. What is the correct mixing procedure for these ingredients to achieve a stable cream texture?

คำตอบ

Hello! Thank you for sharing your formula for an anti-aging, lifting, and brightening cream and your questions. Based on the staff's advice regarding your formulation:

  1. Regarding the use of Light Cream Maker™ (ID 141) with the Centella Asiatica Extract (ID 294):

    • The staff advises that Light Cream Maker™ may not be suitable for this formula, especially because it contains a relatively high amount of electrolytes, such as DMAE (ID 637).
    • Instead, they recommend using Pro Polymer (ID 234). Pro Polymer is more tolerant to electrolytes and can effectively create a gel texture while also helping to emulsify the oil-soluble Centella Asiatica extract into the formula.
  2. Regarding the preservative (Phenoxyethanol, ID 155):

    • The staff confirms that Phenoxyethanol (ID 155) at 1% concentration is suitable for your formula.
    • Alternatively, you could also use Mild Preserved™ (Ethylhexylglycerin, ID 642) at a concentration of 0.8-1.0%.
  3. Regarding the mixing procedure using Pro Polymer (ID 234):

    • Here are the recommended steps:
      • Combine the water-soluble ingredients (Argireline, Matrixyl 3000, DMAE, Vitamin B3, N-Acetyl-D glucosamine, and water) and mix until fully dissolved.
      • Add Pro Polymer (ID 234) to this mixture and stir to form a smooth gel texture.
      • Finally, add the oil-soluble ingredient (Centella Asiatica Extract, ID 294) to the gel and mix thoroughly until a cream texture is achieved.

Your formula includes several excellent active ingredients for your desired effects. Following the staff's recommendation to use Pro Polymer should help ensure a stable and effective cream texture.

Hope this helps!

ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง

Acetyl Hexapeptide-8 (eq Argireline)
Acetyl Hexapeptide-8 (eq Argireline)
เครื่องสำอาง
Pal-GHK, Pal-GQPR (eq Matrixyl 3000)
Pal-GHK, Pal-GQPR (eq Matrixyl 3000)
เครื่องสำอาง
Safe-B3™ (Vitamin B3, Niacinamide)
Safe-B3™ (Vitamin B3, Niacinamide)
เครื่องสำอาง
GlucoBright™ (Acetyl Glucosamine)
GlucoBright™ (Acetyl Glucosamine)
เครื่องสำอาง
Light Cream Maker™
Light Cream Maker™
เครื่องสำอาง
Phenoxyethanol (Extra Pure)
Phenoxyethanol (Extra Pure)
เครื่องสำอาง
Pro Polymer™ (Gel Maker)
Pro Polymer™ (Gel Maker)
เครื่องสำอาง
Centella Asiatica Extract (Madecassoside 7%, Liquid)
Centella Asiatica Extract (Madecassoside 7%, Liquid)
เครื่องสำอาง
DMAE (SkinTight MD™) Liquid
DMAE (SkinTight MD™) Liquid
เครื่องสำอาง
Ethylhexylglycerin
Ethylhexylglycerin
เครื่องสำอาง