Formulation Advice: Eye Irritation, Shea Butter Emulsification, CoQ10, and Melasma Treatment

ถามโดย: shopping.noom เมื่อ: February 01, 2013 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I have several questions regarding cosmetic formulation:

  1. Eye Area Reaction: I made a trial formula containing Water, Shea Butter, Centella Asiatica Extract, Coenzyme Q10, Green Tea Extract, Aloe Vera Extract, Sea Kelp Extract, Phenoxyethanol, and Light Cream Maker™. When applied to the face, there is no sensation, but when applied around the eyes, it feels warm. Why does this happen only around the eyes?
  2. Natural vs. Chemical Ingredients: What are the considerations regarding allergies and sensitivity when choosing between natural and chemical ingredients?
  3. Shea Butter Emulsification: How can I properly incorporate Shea Butter into a formula with water-soluble ingredients like Centella Asiatica Extract, Coenzyme Q10 (oil-soluble), and Green Tea Extract? (I used Light Cream Maker™ in my trial).
  4. Coenzyme Q10 Concentration: Is using Coenzyme Q10 at a concentration higher than the recommended rate harmful? What is the typical effective range?
  5. Mixing Equipment: Where can I find information on the availability of mixing equipment like spoons or heat-resistant glass beakers?
  6. Melasma/Dark Spot Formula pH: For a formula targeting melasma and dark spots using Alpha Arbutin, Kojic Acid, Safe-B3™ (Vitamin B3, Niacinamide), and GlucoBright™ (Acetyl Glucosamine), is significant pH adjustment required? What is the optimal pH range for these ingredients?

คำตอบ

Formulation Advice for Sensitive Skin

Here is some information regarding your questions about formulating cosmetics, focusing on natural ingredients for sensitive skin and addressing specific concerns like eye area issues and melasma.

Eye Cream for Allergy-Prone Skin

For the delicate eye area affected by allergies, focusing on gentle, soothing, and strengthening ingredients is key. While synthetic ingredients like Eyeseryl and Haloxyl are effective for puffiness and dark circles, you can also consider natural extracts known for their calming and beneficial properties:

  • REGU®-AGE: This ingredient is specifically designed to reduce dark circles and puffiness around the eyes by improving microcirculation and protecting collagen and elastin. It also helps strengthen the skin barrier.
  • Pep®-Eye (Acetyl Tetrapeptide-5): A peptide that helps reduce puffiness and dark circles by inhibiting glycation and improving vascular permeability.
  • Centella Asiatica Extract (Gotu Kola): Known for its soothing and skin-repairing properties, it can help reduce inflammation and support collagen production.
  • Sea Kelp Extract: Provides moisture and nourishment, helps balance the skin, and can strengthen sensitive skin while offering antioxidant benefits.
  • Aloe Vera Extract: A classic soothing and moisturizing ingredient that helps reduce irritation and hydrate the skin.
  • Safe-B3™ (Vitamin B3, Niacinamide): Gentle and beneficial for reducing dark circles by improving blood flow, reducing hyperpigmentation, and strengthening the skin barrier. It is suitable for the eye area.

When formulating for sensitive skin, always start with low concentrations and patch test on a small area first.

Adding Shea Butter to Your Formula

To incorporate Shea Butter into your formula with ingredients like Centella Asiatica Extract, Coenzyme Q10, and Green Tea Extract, you need an emulsifier because Shea Butter and Coenzyme Q10 are oil-soluble, while the extracts are water-soluble. You correctly used Light Cream Maker™ in your trial formula, which is designed for this purpose.

General Method:

  1. Prepare your water phase ingredients (Water, Centella Asiatica Extract, Green Tea Extract, Aloe Vera Extract, Sea Kelp Extract, Phenoxyethanol). Mix them well.
  2. Prepare your oil phase ingredients (Shea Butter, Coenzyme Q10). Gently heat the Shea Butter (around 60-70°C) until it melts and mix in the Coenzyme Q10.
  3. Add the Light Cream Maker™ to your oil phase and mix.
  4. Slowly add the oil phase (containing Shea Butter, Coenzyme Q10, and Light Cream Maker™) to the water phase while stirring continuously. The mixture will emulsify and form a cream or lotion.
  5. Continue stirring until the mixture cools down and the desired texture is achieved.

Your experience with the warming sensation around the eyes but not on the face suggests that the skin around your eyes is particularly sensitive, possibly due to allergies. The combination of ingredients, even natural ones, might be too stimulating for that specific area. As advised previously, if the warming persists, it's best to stop using the formula on the eye area and test individual ingredients or simplify the formula.

Coenzyme Q10 Concentration

Regarding Coenzyme Q10, using more than the recommended rate (typically 0.01-0.5% for the oil-soluble powder form) is generally not harmful as it is considered safe, even at high oral doses. However, using concentrations significantly higher than recommended is often unnecessary and can be wasteful. The effectiveness of skincare often relies more on consistent use at appropriate concentrations rather than using very high amounts.

Mixing Equipment

Unfortunately, I cannot provide information on the availability of mixing equipment such as spoons or heat-resistant glass beakers. My capabilities are focused on providing information about cosmetic ingredients and formulation.

Melasma and Dark Spot Formula

For reducing melasma and dark spots, the ingredients you mentioned – Alpha Arbutin, Kojic Acid, Safe-B3™ (Vitamin B3, Niacinamide), and GlucoBright™ (Acetyl Glucosamine) – are indeed effective choices. They work through different mechanisms to inhibit melanin production and improve skin tone.

  • Alpha Arbutin: Inhibits tyrosinase enzyme activity, reducing melanin production.
  • Kojic Acid: Also inhibits tyrosinase activity.
  • Safe-B3™ (Vitamin B3): Reduces melanin transfer to skin cells and helps improve overall skin tone and barrier function.
  • GlucoBright™ (Acetyl Glucosamine): Works synergistically with Vitamin B3 to reduce hyperpigmentation and also helps with skin hydration and gentle exfoliation.

Based on the properties of these ingredients, a formula containing Alpha Arbutin, Kojic Acid, Vitamin B3, and Acetyl Glucosamine generally does not require significant pH adjustment if used within their recommended concentration ranges. The resulting pH should naturally fall within a suitable range (typically around pH 4-7) where these ingredients are stable and effective. Alpha Arbutin is most stable between pH 3.5-6.5, Vitamin B3 between 4.0-7.0, Kojic Acid can work in pH 3-8, and Acetyl Glucosamine in pH 3-7.

Additional Recommended Ingredients for Melasma/Dark Spots:

  • Tranexamic Acid: Helps reduce melanin production and is effective for melasma.
  • MelaninTerminate™: Works via a different mechanism (endothelin antagonist) to inhibit melanin formation.
  • Pep-Even™ (Tetrapeptide-30): Inhibits pigment transfer to keratinocytes, helping to even out skin tone.
  • GlyciWhite™: Counteracts the melanin production process gently.

Combining ingredients with different mechanisms of action can often lead to more effective results in treating hyperpigmentation.

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Alpha Arbutin (Switzerland)
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Safe-B3™ (Vitamin B3, Niacinamide)
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Aloe Vera Extract (extraction ratio 10:1 FullAssay™)
Aloe Vera Extract (extraction ratio 10:1 FullAssay™)
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Sea Kelp Extract
Sea Kelp Extract
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GlucoBright™ (Acetyl Glucosamine)
GlucoBright™ (Acetyl Glucosamine)
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Shea Butter (Refined , Deodorised)
Shea Butter (Refined , Deodorised)
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Ethoxydiglycol (e.q. Transcutol)
Ethoxydiglycol (e.q. Transcutol)
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Light Cream Maker™
Light Cream Maker™
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Kojic Acid Dipalmitate
Kojic Acid Dipalmitate
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Phenoxyethanol (Extra Pure)
Phenoxyethanol (Extra Pure)
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REGU®-AGE (CB)
REGU®-AGE (CB)
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Centella Asiatica Extract (Madecassoside 90%)
Centella Asiatica Extract (Madecassoside 90%)
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Tranexamic Acid (Trans-White™)
Tranexamic Acid (Trans-White™)
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Pep®-Eye (Acetyl Tetrapeptide-5)
Pep®-Eye (Acetyl Tetrapeptide-5)
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GlyciWhite™
GlyciWhite™
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MelaninTerminate™
MelaninTerminate™
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Pep-Even™ (Tetrapeptide-30)
Pep-Even™ (Tetrapeptide-30)
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