Formulation Review

Regarding the formulation you provided:

• Aloe Vera Gel Heavy: 84%
• Argireline: 10%
• Pep Coll: 3%
• DMAE: 3%

Based on the information available for these ingredients:

• Compatibility: The active ingredients (Argireline, Pep Coll, and DMAE) are water-soluble liquids and can generally be mixed into a water-based gel like Aloe Vera Gel. They should be added in the final phase of mixing, ensuring the temperature is below 40°C.
• Usage Rates: The concentrations you propose (10% Argireline, 3% Pep Coll, 3% DMAE) are within the recommended usage ranges for these specific ingredients.
• Potential Irritation: While DMAE at 3% is within the recommended range, it's noted that concentrations above 5% may cause irritation, and even at 3%, it might not be suitable for thin or sensitive skin. Consider your skin type and potentially add ingredients that help reduce irritation if needed.
• pH Consideration: Argireline requires the final formulation pH to be within the range of 3.5-6.5 for optimal stability and efficacy. You would need to check and adjust the pH of your final mixture to ensure it falls within this range.

Important Considerations:

While the ingredients appear compatible based on their general properties and recommended mixing instructions, creating a stable and effective cosmetic product requires careful formulation and testing. Factors like long-term stability, preservation, and skin feel should also be considered.

It is recommended to perform small-scale tests first to check for stability, appearance, and skin reaction before making a larger batch.