Formulation Compatibility and Irritation Reduction for Acne

Asked by: sukontip0204 On: December 17, 2020 Product Type: Cosmetics

Question

Ingredients:

  • Rhamnose 3%
  • Liquid Azelaic 10%
  • Panthenol 1%
  • Mild Preserved Eco 1%
  • Satin Cream Maker 1%
  • Distilled Water remaining part
    Are these ingredients compatible? Can this formula help reduce irritation from acne medication?

Answer

Formulation Compatibility and Irritation Reduction

Based on the ingredients provided, this formulation appears compatible and contains components that can help reduce irritation, especially when used alongside acne treatments.

Here's a breakdown:

  • Compatibility: The ingredients listed are generally compatible. Rhamnose, Liquid Azelaic, and Panthenol are water-soluble and can be incorporated into the water phase. Satin Cream Maker is a heat-free emulsifier added to the water phase, suitable for creating a cream or serum-cream texture with the water and other ingredients. Mild Preserved Eco is added in the final step and is compatible with the pH range and mixing method.
  • Reducing Irritation: The formulation includes key ingredients known for their soothing and skin-calming properties:
    • Panthenol (Vitamin B5): This ingredient is excellent for moisturizing, strengthening the skin barrier, reducing inflammation, redness, and itching, and promoting wound healing. It is specifically noted as ideal for acne-prone skin and helping to reduce inflammation.
    • Rhamnose: This sugar molecule has been shown to reduce inflammation and redness on the skin.
    • Liquid Azelaic: While Azelaic Acid itself can sometimes cause irritation, the Liquid Azelaic™ form (Potassium azeloyl diglycinate) is a special water-soluble type designed to be gentler than standard Azelaic Acid. At 10%, it is used for its effectiveness in reducing oiliness, clogged pores, and brightening the skin, while being less irritating than traditional forms.

Combining Panthenol and Rhamnose in this formula provides significant benefits for soothing the skin and helping to counteract potential irritation, including that from other acne medications. The Liquid Azelaic also contributes to acne treatment in a gentler way.