Formulation Compatibility Check
Question
I would like to inquire about the compatibility of the following formulation:
- Repair Activator 15%
- Double Hyaluron Liquid 10%
- Perfect-C 5%
- Yeast Radiance 3%
- Marine Plankton 3%
- Yeast Resurface 3%
- Lactobacillus Ferment Lysate 3%
- Ectoine (Ectoin) 2%
- WaterLock 2%
- PiteraEx 1%
- Base: Aloe Vera Gel (Lite)
Are these ingredients compatible when mixed together?
Answer
Formulation Compatibility Analysis
Based on the ingredients and percentages provided, there are significant compatibility issues that would prevent this formulation from being stable and effective as listed.
Key Issues:
Incompatibility between Aloe Vera Gel (Lite) and Double Hyaluron Liquid: The description for Aloe Vera Gel (Lite) explicitly states that it is incompatible with Hyaluronic Acid (Nano and Standard types) and Double Hyaluron Gel/Liquid. Since Double Hyaluron Liquid contains both Nano and Standard Hyaluronic Acid, these two main components of your formulation base and active ingredients cannot be mixed together directly. This is the primary reason the formulation will not work.
Perfect-C (Ascorbyl Tetraisopalmitate) is Oil-Soluble: Perfect-C is an oil-soluble form of Vitamin C. The base you are using, Aloe Vera Gel (Lite), is a water-based gel. Mixing an oil-soluble ingredient into a water-based gel without a proper emulsifying system will cause the ingredients to separate and the formulation will not be stable or homogenous.
Marine Plankton Usage Rate: The suggested usage rate for Marine Plankton is 1-2%, but you are proposing to use it at 3%. While this might not cause a direct incompatibility, using a higher percentage than recommended could potentially affect the texture or stability of the final product, in addition to the other compatibility problems.
pH Considerations: Many of the active ingredients have specific optimal pH ranges (e.g., Repair Activator pH 4-5.5, Lactobacillus Ferment Lysate pH 3.5-5.5, Perfect-C pH 5.0-5.5). Achieving a single stable pH that is optimal for all these ingredients is challenging, and the incompatibility issues mentioned above make pH adjustment and stability even more difficult.
Conclusion:
The proposed formulation is not compatible due to the direct conflict between the Aloe Vera Gel (Lite) base and the Double Hyaluron Liquid, as well as the challenge of incorporating the oil-soluble Perfect-C into a water-based system without an emulsifier. The formulation will likely separate.
To create a stable product with these active ingredients, you would need to revise the base significantly, potentially using a different type of base that is compatible with hyaluronic acid or formulating it as an emulsion (cream or lotion) that can incorporate both water-soluble and oil-soluble ingredients with the help of emulsifiers.
Related Products Mentioned
WaterLock™ (Polyquaternium-51)
Double Hyaluron Liquid
Perfect-C™ (Ascorbyl Tetraisopalmitate)
Aloe Vera Gel (Lite)
Yeast Resurface
Yeast Radiance™
Ectoine (Ectoin, from Bio-fermentation)
Marine Plankton (Lifting, Tightening)
Dermal Respiratory Factor