Formulation Examples: Carbamide Peroxide, Hydroxyapatite, Sodium Fluoride for Dental Care

Asked by: thesunlaboratory On: August 29, 2021 Product Type: Cosmetics

Question

I would like to know about example formulations for [url=https://www.myskinrecipes.com/shop/%E0%B8%9F%E0%B8%AD%E0%B8%81%E0%B8%9F%E0%B8%B1%E0%B8%99%E0%B8%8ข%E0%B8%B2%E0%B8%A7/9086-carbamide-peroxide-44-gel.html:2ddt57uo]Carbamide Peroxide[/url:2ddt57uo] (44%), [url=https://www.myskinrecipes.com/shop/%E0%B8%9A%E0%B8%B3%E0%B8%A3%E0%B8%B8%E0%B8%87%E0%B8%8A%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B9%80%E0%B8%9B%E0%B8%B2%E0%B8%81/7761-hydroxyapatite-hydroxylapatite-nano.html:2ddt57uo]Hydroxyapatite[/url:2ddt57uo], and [url=https://www.myskinrecipes.com/shop/%E0%B8%9A%E0%B8%B3%E0%B8%A3%E0%B8%B8%E0%B8%87%E0%B8%8A%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B9%80%E0%B8%9B%E0%B8%B2%E0%B8%81-%E0%B9%80%E0%B8%9B%E0%B9%89%E0%B8%AD%E0%B8%81%E0%B8%B1%E0%B8%99%E0%B8%9D%E0%B8%B1%E0%B8%99%E0%B8%9C%E0%B8%B8/7662-sodium-fluoride-for-oral-care.html:2ddt57uo]Sodium Fluoride[/url:2ddt57uo] for dental care purposes, specifically for preventing cavities, enamel coating, and teeth whitening. Could you please provide example formulations and mixing methods? Thank you.

Answer

Example Ingredients for Dental Care Formulations

Here is information on the ingredients you asked about and how they are typically used in dental care formulations for preventing cavities, enamel coating, and teeth whitening.

Teeth Whitening

Carbamide Peroxide is a standard ingredient for teeth whitening. It works by releasing hydrogen peroxide when it comes into contact with moisture.

  • There are different forms available, such as a 25% gel or a 95% solid.
  • The 95% solid form must be diluted, typically using Glycerin or Propylene Glycol, to a concentration suitable for cosmetic use (e.g., not exceeding 17% Carbamide Peroxide). Water should not be used for dilution.
  • When formulating, Carbamide Peroxide is blended evenly into the recipe, often to create a gel.

Enamel Coating and Remineralization

Hydroxyapatite and Fluoro-hydroxyapatite are substances that are naturally found in tooth enamel and bone. They are used in oral care products to help restore and strengthen the tooth surface (remineralization) and can help coat the enamel.

  • These ingredients are typically white powders that are dispersed, not dissolved, in the formulation base (like toothpaste or a paste).
  • Recommended usage rates are generally between 5% and 10%.
  • An example paste formulation for tooth remineralization using Fluoro-hydroxyapatite involves dispersing 10% of the powder in distilled water with a preservative.

Preventing Cavities

Sodium Fluoride is commonly used in dental care products for its effectiveness in preventing tooth decay (anticaries).

  • It is a white powder that is soluble in water.
  • It can be incorporated into various oral care products such as mouthwash, toothpaste, and sprays.
  • There are regulations on the maximum allowed concentration of Sodium Fluoride in cosmetic oral hygiene products (e.g., 0.15% calculated as fluorine in the EU).

Formulation Considerations

Creating a stable and effective dental care product requires careful formulation beyond simply combining these ingredients. Factors such as ingredient compatibility, pH stability, viscosity, and the inclusion of other necessary components (like thickeners, flavors, and preservatives) must be considered. The information above provides guidance on the properties and typical usage ranges of the specific ingredients you mentioned, but a complete formulation requires detailed development and testing.