Formulation Feasibility: Resveratrol 3% + Ferulic Acid 3% in 1,3-Propanediol 94%

Regarding your proposed formula of 94% 1,3-Propanediol, 3% Resveratrol, and 3% Ferulic Acid, it is important to consider the solubility of the active ingredients.

Based on the product information:

• Trans-Resveratrol (Powder, 98%) is soluble in organic solvents like ethanol but not in water.
• Pure-Ferulic Acid™ is soluble in solvents like Ethoxydiglycol or ethanol but not in water.
• Propanediol (1,3-Propanediol) is a water-soluble solvent.

Since the powder forms of Resveratrol and Ferulic Acid are not water-soluble, using 94% 1,3-Propanediol as the primary solvent may not be able to fully dissolve 3% of each active ingredient, potentially leading to an unstable or cloudy solution. The recommended usage rate for Pure-Ferulic Acid™ powder is also typically lower, at 0.5-1%.

To achieve a stable solution with these concentrations, you would likely need to use a different solvent system that is compatible with the powder forms of Resveratrol and Ferulic Acid, or consider using alternative forms of these ingredients.

Alternatively, you could explore using the microemulsion forms:

• Micromul™ Resveratrol (a microemulsion liquid) is water-soluble and can be dissolved in water or water-soluble solvents like 1,3-Propanediol. However, this product contains a minimum of 4% Trans-Resveratrol, meaning you would need to use a higher percentage of the microemulsion product itself to reach 3% actual Resveratrol in your final formula (approximately 75% of Micromul™ Resveratrol).
• Micromul™ Ferulic Acid (a microemulsion liquid) is also water-soluble and can be dissolved in water. The recommended usage rate for this form is 1-5% (typically 2-3%).

If you use the microemulsion forms, they can be dissolved in 1,3-Propanediol. However, achieving the exact 3% concentration of the active ingredients while keeping 1,3-Propanediol at 94% would require careful calculation based on the actual concentration of the active in the microemulsion product.

In summary, directly mixing 3% powder Resveratrol and 3% powder Ferulic Acid into 94% 1,3-Propanediol is likely not feasible due to solubility issues. You would need to adjust the solvent system or use different forms of the active ingredients.