Vitamin B3 and Vitamin B5 Formulation Guidance

It appears the link you received for the formulation recipe is not working. Based on your ingredients, which include Vitamin B3 (Niacinamide) and Vitamin B5 (likely in the form of a precursor like Pantolactone), here is some guidance on how to use these beneficial ingredients in a formulation.

About the Ingredients

• Safe-B3™ (Vitamin B3, Niacinamide): This ingredient is excellent for reducing wrinkles, improving hyperpigmentation, boosting skin hydration by stimulating ceramide production, strengthening the skin barrier, reducing oiliness, and offering anti-inflammatory and anti-aging benefits. It is typically used at a rate of 1-10%, with the Safe-B3™ type being usable up to 10% without causing flushing. It is water-soluble and should be mixed into the water phase of your formulation. The optimal pH range is 3-8, ideally 4.0-7.0.

• PreB5™ (Pantolactone, Pantoyl Lactone): Pantolactone is a precursor to Vitamin B5 (Pantothenic Acid) and is known for its highly effective moisturizing properties, helping to strengthen skin hydration. It is typically used at a rate of 0.5-1.0%, with 1% being recommended for best results. It is also water-soluble and should be mixed into the water phase.

General Formulation Guidance

Since both Vitamin B3 (Niacinamide) and PreB5™ (Pantolactone) are water-soluble, they can be easily incorporated into water-based formulations like serums, toners, or light lotions.

A simple approach would be to create a water-based serum:

1. Water Phase: Combine distilled water with your desired percentage of Safe-B3™ (e.g., 5-10%) and PreB5™ (e.g., 1%). You may also add other water-soluble ingredients like humectants (e.g., Glycerin, Propanediol) for added hydration.
2. Thickening (Optional): If you desire a thicker serum consistency, you can add a water-soluble thickener (e.g., Carbomer, Xanthan Gum) to the water phase and neutralize it if required.
3. Preservation: It is crucial to add a broad-spectrum preservative system to prevent microbial growth, as water-based formulations are prone to contamination.
4. Adjust pH: After adding all ingredients except the preservative (some preservatives require pH adjustment beforehand), check and adjust the pH to the optimal range for Niacinamide (4.0-7.0) using a pH adjuster (e.g., Lactic Acid or Sodium Hydroxide solution).
5. Add Preservative: Incorporate your chosen preservative according to the supplier's instructions.

Always ensure ingredients are fully dissolved and the mixture is homogeneous. Start with small batch sizes if you are new to formulating.

This guidance should help you utilize your Safe-B3™ and PreB5™ ingredients effectively. For a complete, specific recipe, you would need the details from the original source.