Gel and Cream Formulation with Actives: Feasibility, Mixing, and Adding Moisturizers

ถามโดย: luknoo1989 เมื่อ: January 08, 2018 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I would like to create two cosmetic formulas, a gel and a cream, using the following ingredients. Could you please review the formulas for feasibility and provide guidance on the mixing procedure, especially regarding the order of adding ingredients like Zinc PCA? Additionally, I plan to make a similar formula for normal skin and would like to know if I can add Panthenol, Rice Vitamin (Inositol), and L-Carnitine, and how to incorporate them.

Gel Formula:

  • B3 (Niacinamide) 4%
  • NAG (Acetyl Glucosamine) 4%
  • Zinc PCA 1%
  • Beta Glucan 7%
  • Pitera (Galactomyces Ferment Filtrate) 30%
  • Phenoxyethanol SA 0.6%
  • Pro Polymer (Acrylate Crosspolymer) 2%
  • Rhamnose 3%
  • DI Water (remaining proportion)

Cream Formula:

  • Water Phase:
    • B3 (Niacinamide) 4%
    • NAG (Acetyl Glucosamine) 4%
    • Zinc PCA 1%
    • Beta Glucan 7%
    • Pitera (Galactomyces Ferment Filtrate) 20%
    • Phenoxyethanol SA 0.6%
    • Rhamnose 3%
    • Satin Cream Maker (Silky Cream Maker) 1%
  • Oil Phase:
    • Coenzyme Q10 Extra 1%
    • MSH White Absorb 5%
    • Pro-Niacin (Myristyl Nicotinate) 5%

Specific Questions:

  1. Are both formulas feasible to mix as listed?
  2. What is the correct mixing procedure for each formula, particularly noting any sensitive ingredients or specific addition orders (like Zinc PCA)?
  3. Can I use a magnetic bar and stirrer for mixing?
  4. For a formula targeting normal skin needing more moisture, can I add Panthenol, Rice Vitamin (Inositol), and L-Carnitine? How should these be added?

คำตอบ

Formula Analysis

Overall, both of your formulas contain excellent ingredients targeting your desired properties: reducing oiliness and acne, providing hydration, anti-aging benefits, brightening, and strengthening the skin barrier. Ingredients like Niacinamide (Safe-B3™), Acetyl Glucosamine (GlucoBright™), Zinc PCA, Beta Glucan, Pitera (Galactomyces Ferment Filtrate), Rhamnose, Coenzyme Q10, MSH White™, and Myristyl Nicotinate (Max-B3™) are all well-suited for these goals.

However, there are a few points to consider regarding the concentration and mixing of certain ingredients, as noted in the staff reply and product descriptions.

Gel Formula

  • Ingredients: Safe-B3™ (Niacinamide) 4%, GlucoBright™ (NAG) 4%, Zinc PCA 1%, Beta Glucan 7%, Pitera (Galactomyces Ferment Filtrate) 30%, Phenoxyethanol SA 0.6%, Pro Polymer™ 2%, Rhamnose 3%, DI Water.
  • Analysis:
    • The active ingredients are appropriate for your skin type and goals.
    • As the staff mentioned, the concentration of Pro Polymer™ at 2% is likely too high and will result in a very thick, potentially pudding-like gel texture, which might feel sticky and not ideal for combination skin seeking a non-greasy feel. Reducing Pro Polymer™ to 1.0-1.3% should be sufficient to create a gel texture.
    • The high concentration of Pitera (30%) is within the usage range but might contribute to a slightly greasy feel, as noted in its description.
    • The mixing order for Zinc PCA is crucial. It is an electrolyte and should be added gradually after the gel texture has formed with Pro Polymer™ to avoid interfering with gel formation.
    • Ensure the final pH of the formula is in the optimal range for the ingredients, ideally between 4-6, which is suitable for Zinc PCA, Niacinamide, and Acetyl Glucosamine, and compatible with Phenoxyethanol SA (pH 2-6) and Rhamnose (pH 5-9).
  • Expected Results: This formula should be effective for acne, oil control, brightening, anti-aging, and barrier support. However, the texture might be thicker and potentially stickier than desired due to the Pro Polymer™ and high Pitera concentration. Adjusting Pro Polymer™ is recommended for a better feel.

Cream Formula

  • Ingredients: Water Phase: Safe-B3™ 4%, GlucoBright™ 4%, Zinc PCA 1%, Beta Glucan 7%, Pitera 20%, Phenoxyethanol SA 0.6%, Rhamnose 3%, Satin Cream Maker™ 1%. Oil Phase: Coenzyme Q10 (Oil-Soluble) 1%, MSH White™ 5%, Max-B3™ (Myristyl Nicotinate) 5%.
  • Analysis:
    • Again, the ingredient selection is good for your goals.
    • The staff correctly pointed out that 1% Satin Cream Maker™ is likely insufficient to emulsify the oil phase, especially with the presence of Zinc PCA (an electrolyte) which can reduce the effectiveness of Satin Cream Maker™. Increasing Satin Cream Maker™ to at least 2.0% or adding 1% Pro Polymer™ alongside 1% Satin Cream Maker™ is necessary for stable emulsification.
    • The usage rate for Coenzyme Q10 (1%) is higher than the recommended maximum of 0.5%. While it might not cause issues, it's worth noting.
    • The usage rate for MSH White™ (5%) is significantly higher than the recommended maximum of 0.5-2%. Using such a high concentration might not provide additional benefits and could potentially cause formulation issues or irritation. It's generally recommended to stick within the suggested usage rates for optimal performance and safety.
    • MSH White™ and Coenzyme Q10 are oil-soluble and need to be dissolved in the oil phase, requiring heating to around 80°C for MSH White™ and below 60°C for Coenzyme Q10. This needs to be factored into your mixing process. Max-B3™ is also oil-soluble and should be mixed in the oil phase.
    • Ensure the final pH is in the optimal range (4-6) for the water-soluble actives, which is compatible with Satin Cream Maker™ (pH 3-12), Phenoxyethanol SA (pH 2-6), and Rhamnose (pH 5-9).
  • Expected Results: This formula has the potential to address your goals, but the stability of the emulsion is questionable with only 1% Satin Cream Maker™. Adjusting the emulsifier system is necessary. The high concentrations of CoQ10 and MSH White™ might be unnecessary and could potentially cause issues.

Mixing Method

Yes, you can use a magnetic bar and a stirrer (like an overhead stirrer) for mixing these formulas.

  • For the gel formula, a magnetic stirrer is generally sufficient for mixing the water phase and incorporating the Pro Polymer™. Remember to add the Pro Polymer™ gradually and stir slowly initially, avoiding high shear mixing (>2500 rpm) to prevent damaging the polymer structure. Add Zinc PCA last, slowly, while stirring.
  • For the cream formula, a magnetic stirrer with a heating plate or an overhead stirrer with a heating bath would be suitable. You will need to heat the oil phase to dissolve the oil-soluble ingredients (MSH White™ and Coenzyme Q10) before combining it with the water phase. When combining the phases and emulsifying with Satin Cream Maker™, use moderate stirring and avoid excessive speed (>2500 rpm) to ensure a stable emulsion.

Adding Ingredients for Normal Skin

Yes, you can add Panthenol (PreB5™), Rice Vitamin (Inositol), and L-Carnitine to a formula for normal skin seeking more moisture.

  • Panthenol (PreB5™): A good moisturizer and skin strengthener. It is water-soluble and can be added to the water phase at a recommended rate of 0.5-1.0%.
  • Rice Vitamin (Inositol): Helps balance skin moisture and is suitable for both combination and dry skin. It is water-soluble and can be added to the water phase at a recommended rate of 1-3%.
  • L-Carnitine: Provides moisture balance, accelerates cell turnover, and helps reduce oiliness. It is water-soluble and can be added to the water phase at a recommended rate of 1-5%. It is sensitive to moisture, so handle with care.

These ingredients are water-soluble and compatible with the pH ranges of the ingredients in your existing formulas. Adding them will increase the total percentage of water-soluble actives, which might require a slight adjustment (increase) in the amount of your gel maker (Pro Polymer™) or emulsifier (Satin Cream Maker™) to maintain the desired texture and stability.

Summary and Recommendations

  • Your ingredient choices are appropriate for the desired benefits.
  • For the gel formula, reduce the Pro Polymer™ concentration to achieve a less thick, non-sticky texture (aim for 1.0-1.3%). Add Zinc PCA after the gel has formed.
  • For the cream formula, increase the Satin Cream Maker™ concentration to at least 2.0% or use a combination of Satin Cream Maker™ and Pro Polymer™ (e.g., 1% each) to ensure a stable emulsion. Reconsider the high concentrations of Coenzyme Q10 and MSH White™ and potentially reduce them to the recommended maximums for better formulation stability and cost-effectiveness. Ensure MSH White™ and CoQ10 are properly dissolved in the oil phase with heat before emulsification.
  • Magnetic stirrers and overhead stirrers are suitable mixing equipment, but avoid high shear (>2500 rpm) when incorporating thickeners/emulsifiers.
  • Panthenol, Rice Vitamin, and L-Carnitine can be added to formulas for normal skin needing more moisture; add them to the water phase. Be mindful that adding more water-soluble ingredients might necessitate adjusting the thickener/emulsifier concentration.

ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง

Safe-B3™ (Vitamin B3, Niacinamide)
Safe-B3™ (Vitamin B3, Niacinamide)
เครื่องสำอาง
GlucoBright™ (Acetyl Glucosamine)
GlucoBright™ (Acetyl Glucosamine)
เครื่องสำอาง
L-Carnitine (Carnitine)
L-Carnitine (Carnitine)
เครื่องสำอาง
Beta Glucan (Saccharomyces cerevisiae extract)
Beta Glucan (Saccharomyces cerevisiae extract)
เครื่องสำอาง
Pro Polymer™ (Gel Maker)
Pro Polymer™ (Gel Maker)
เครื่องสำอาง
Satin Cream Maker™
Satin Cream Maker™
เครื่องสำอาง
Zinc PCA
Zinc PCA
เครื่องสำอาง
Galactomyces Ferment Filtrate (aka Pitera)
Galactomyces Ferment Filtrate (aka Pitera)
เครื่องสำอาง
Rice Vitamin (Inositol, Vitamin B8)
Rice Vitamin (Inositol, Vitamin B8)
เครื่องสำอาง
MSH White™ (Undecylenoyl phenylalanine)
MSH White™ (Undecylenoyl phenylalanine)
เครื่องสำอาง
Coenzyme Q10 (98%, Powder, Oil-Soluble)
Coenzyme Q10 (98%, Powder, Oil-Soluble)
เครื่องสำอาง
Rhamnose (rhamnose sugar)
Rhamnose (rhamnose sugar)
เครื่องสำอาง
Phenoxyethanol SA (eq. Optiphen Plus)
Phenoxyethanol SA (eq. Optiphen Plus)
เครื่องสำอาง
PreB5™ (Pantolactone, Pantoyl Lactone)
PreB5™ (Pantolactone, Pantoyl Lactone)
เครื่องสำอาง
Max-B3™ (Myristyl Nicotinate, e.q. NIA-114)
Max-B3™ (Myristyl Nicotinate, e.q. NIA-114)
เครื่องสำอาง