Gel Formulation for Mature, Dry Skin with Wrinkles and Freckles

Thank you for your question regarding a gel formulation for your mother's skin concerns. Based on the ingredients you've selected, this formula targets dryness, deep wrinkles, and freckles effectively.

Here's a look at the key ingredients and their benefits:

• Allantoin: Helps soothe the skin and supports tissue regeneration, beneficial for dry and potentially irritated skin.
• GlucoBright™ (Acetyl Glucosamine): Works to reduce dark spots and freckles while also boosting skin hydration by stimulating hyaluronic acid production. It pairs well with Vitamin B3.
• Safe-B3™ (Vitamin B3, Niacinamide): A versatile ingredient that improves the appearance of wrinkles and dark spots, strengthens the skin barrier, and provides moisture.
• DMAE (SkinTight MD™) Liquid: Known for its skin-tightening effects and ability to reduce the appearance of wrinkles.
• MOIST72™: Provides intense and long-lasting hydration, which is crucial for dry skin.
• Acetyl Hexapeptide-8 (eq Argireline): Specifically targets expression lines, like those on the forehead and between the brows, by reducing muscle tension.
• Pal-GHK, Pal-GQPR (eq Matrixyl 3000): Stimulates collagen production, helping to reduce wrinkles and improve skin elasticity. It complements the action of Argireline.
• Snail Secretion: Aids in skin regeneration, moisturizes, and helps improve skin elasticity and texture.

You mentioned concern about the total concentration and potential stickiness. For mature and dry skin, a slightly richer texture can actually be beneficial as it provides necessary hydration and a comfortable feel. While the total percentage of actives is high, the specific ingredients and their roles are well-suited for addressing multiple signs of aging and dryness.

Regarding the concentrations:

• Your proposed concentrations for Allantoin (0.2-0.5%), GlucoBright™ (4%), Safe-B3™ (5%), DMAE (4%), MOIST72™ (4%), Argireline (10%), and Snail Secretion (4%) are generally within or close to the recommended usage rates for these ingredients.
• For Pal-GHK, Pal-GQPR (eq Matrixyl 3000), the recommended usage rate is typically 3-5%. While 8% is proposed, using it at the recommended 5% should still provide significant benefits for collagen stimulation and wrinkle reduction, and could help manage the overall texture of the gel.

Using a suitable gel base like Tester - Pure Aloe Vera Gel is a good starting point. Ensure all ingredients are properly dissolved and mixed according to their specific instructions (e.g., adding heat-sensitive ingredients in the final step below 40°C).

Given the high concentration of active ingredients, especially DMAE which can cause irritation in sensitive individuals or at higher levels, it is highly recommended to perform a patch test on a small area of skin before applying the gel to the entire face.

This formulation combines powerful ingredients to address your mother's specific concerns, focusing on hydration, wrinkle reduction, and improving skin tone.