GHK-Cu Serum Formulation Guide and Compatibility Tips
ถามโดย: ไม่ระบุชื่อ
เมื่อ: September 28, 2025
ประเภทผลิตภัณฑ์:
เครื่องสำอาง
คำถาม
What are the instructions and key technical considerations for formulating an effective GHK-Cu (Copper Peptide) serum? Specifically, please provide guidance on:
- Recommended product forms (e.g., solution vs. powder) for ease of formulation.
- A simple formulation guide, including recommended usage percentages for
GHK-Cu 10000ppm Solutionto achieve an effective concentration (0.05% to 0.1% pure peptide). - Critical formulation tips regarding processing temperature, final product pH requirements (optimal pH range of 5.0 to 7.0), and known ingredient incompatibilities, particularly concerning strong acids like L-Ascorbic Acid (pure Vitamin C).
คำตอบ
Yes, we can provide instructions on how to create an effective GHK-Cu serum. The key to an effective serum is using the correct concentration and ensuring proper compatibility with other ingredients.
Recommended GHK-Cu Products
We offer GHK-Cu in various forms. For ease of use in a serum, the pre-dissolved solutions are recommended:
- Copper Peptide (GHK-Cu, Copper Tripeptide-1) (10000ppm Solution) (Product ID: 35807): Contains 1% active GHK-Cu. This is the most convenient option for a potent serum.
- Copper Peptide (GHK-Cu, Copper Tripeptide-1) (1000ppm Solution) (Product ID: 272): Contains 0.1% active GHK-Cu. Requires a higher usage rate.
- Copper Peptide (GHK-Cu Copper Tripeptide-1, 1:1) Powder (Product ID: 875): For advanced formulators who prefer to dissolve the powder themselves.
Simple GHK-Cu Serum Formulation Guide
A typical effective concentration for GHK-Cu in a final product is 0.05% to 0.1% of the pure peptide.
| Ingredient | Function | Recommended % (Using 10000ppm Solution) |
|---|---|---|
| Part A (Water Phase) | ||
| Distilled/Deionized Water | Solvent | Balance to 100% |
| Humectant (e.g., Glycerin, Propanediol) | Hydration | 3.0 - 5.0% |
| Thickener (e.g., Xanthan Gum) | Texture | 0.1 - 0.3% |
| Part B (Active & Preservative) | ||
| GHK-Cu 10000ppm Solution | Active | 5.0 - 10.0% |
| Preservative (e.g., Phenoxyethanol) | Preservation | 0.5 - 1.0% |
Instructions:
- Prepare Part A: Heat the water phase (Water, Humectant) to about 70°C. Slowly sprinkle the thickener (Xanthan Gum) into the vortex while stirring vigorously until fully hydrated and a uniform gel forms. Cool to below 40°C.
- Add Part B: Once the mixture is cool, add the GHK-Cu 10000ppm Solution and the preservative. Stir well until fully incorporated.
- Adjust pH: Check the final pH. GHK-Cu is most stable and effective in the pH range of 5.0 to 7.0. Adjust with a small amount of Citric Acid (to lower pH) or Triethanolamine (to raise pH) if necessary.
Critical Formulation Tips
- Compatibility: GHK-Cu should not be formulated with strong acids, especially L-Ascorbic Acid (pure Vitamin C), as this can destabilize the peptide and the Vitamin C.
- Mixing: Always add the GHK-Cu solution to the cooled final product base. Do not heat the peptide.
- Color: The serum will have a light blue tint due to the copper complex. This is normal.
