Heat Resistance of Cyclopentasiloxane and Hyaluronic Acid

Here is information regarding the heat resistance of Cyclopentasiloxane and Hyaluronic Acid:

• Cyclopentasiloxane (Low-Odor Cyclomethicone): Cyclopentasiloxane is a lightweight, volatile silicone. While it should be stored away from direct sunlight and heat to maintain its quality over time, formulations containing Cyclopentasiloxane can often withstand some heat during processing. However, prolonged exposure to high temperatures, such as 70-80°C, is generally avoided during formulation to minimize evaporation of the Cyclopentasiloxane, which could affect the final product composition and performance. It is typically added during the cool-down phase of a formulation.

• Hyaluronic Acid: Based on the information available for Hyaluronic Acid (Standard Molecule) and Hyaluronic Acid (Large Molecule), Hyaluronic Acid should not be exposed to temperatures exceeding 70°C to prevent it from losing its quality. Therefore, temperatures in the range of 70-80°C would likely cause degradation of Hyaluronic Acid.

In summary, Hyaluronic Acid has a clear temperature limit of 70°C for processing, while Cyclopentasiloxane, being volatile, is best incorporated avoiding prolonged high heat, although formulations containing it may tolerate some heat.