How to Use and Mix Glutathione Powder into Existing Body Lotion: Solubility and Stability
Question
I have Glutathione (L-Glutathione Reduced) 99% powder.
- How should this ingredient be used?
- If I already have an existing commercial body lotion (e.g., Vaseline), what is the correct method for mixing the powder into the lotion for use?
- What solvents are suitable for dissolving this ingredient?
Answer
The product Glutathione (L-Glutathione Reduced) (ID: 32425) is a high-purity powder used as an antioxidant and skin-whitening agent.
1. Solvents (สารทำละลาย)
The primary and recommended solvent for this Glutathione powder is Water.
- It is water-soluble.
- You can use heat (60-70°C) for a short period to help it dissolve faster, but the final formula temperature must be kept below 40°C.
2. How to Use and Mix into Existing Lotion (e.g., Vaseline)
CRITICAL WARNING: It is not recommended to mix powdered active ingredients, even if dissolved, into a finished, commercial body lotion (like Vaseline). This practice can lead to several problems:
- Destabilization: It can break the lotion's emulsion, causing it to separate or change texture.
- Rapid Deterioration: Glutathione is highly sensitive to pH and heat. It requires a specific pH range of 3-6 for stability. The pH of commercial lotions is often higher (around 6-7), which will cause the Glutathione to degrade quickly and become ineffective.
- Contamination: Adding external ingredients can compromise the preservative system of the finished product, leading to microbial growth.
The Correct Method (for professional formulation):
Glutathione should be incorporated during the manufacturing process of the lotion. It must be:
- Dissolved in the water phase.
- Added to the formula after the emulsion has formed and cooled down to below 40°C.
- The final formula's pH must be adjusted to the stable range of 3-6.
- The recommended usage rate is 1-3%.
Practical Method (for immediate, small-batch use):
If you insist on using it with an existing cream, you must only mix a small amount immediately before application, as the stability cannot be guaranteed:
- Dissolve: Take a small amount of Glutathione powder (e.g., a pinch) and dissolve it completely in a few drops of clean water.
- Mix: Take a small amount of your Vaseline lotion (enough for one application) and thoroughly mix the Glutathione solution into it.
- Use Immediately: Apply the mixture immediately. Do not mix a large batch to store, as the Glutathione will quickly lose its efficacy.
Related Products Mentioned
