Ingredient Compatibility and pH in Cosmetic Formulations

Based on the list of ingredients provided, the primary compatibility consideration is with AcnePLEX™.

AcnePLEX™ is formulated with a positive charge to enhance its adherence to the skin. This characteristic means it has limitations when combined with negatively charged cream makers or gel makers, as these can cause incompatibility issues in your formulation. When using AcnePLEX™ in a gel or cream, it is crucial to select non-ionic gel makers (such as HEC or HPMC) to ensure stability and effectiveness.

For the other ingredients:

• Azelaic Acid (Liquid Azelaic™): This ingredient is stable within a pH range of 5-11.
• Licorice Extract (Licochalcone A 1%, Water-Soluble): This extract requires the formula to have a pH in the range of 3.5-6.5 for optimal stability.
• Natural Make-Up Amino Acids (e.q. Prodew 700): This ingredient is most stable within a pH range of 4.0-7.5.
• Mild Preserved Eco™: This preservative can be used in cosmetic formulas with a pH range of 4-9.

To ensure compatibility across all these pH-sensitive ingredients, we recommend formulating your product within a pH range of 5.0 to 6.5. This range accommodates the requirements of Azelaic Acid, Licorice Extract, Natural Make-Up Amino Acids, and Mild Preserved Eco™.

QuikBlur™, Micromul™ 10HDA, Mineral Ready™, Hexylresorcinol AF, and Tea Tree Water are generally compatible with a wide range of formulations and do not present specific incompatibility concerns with the other ingredients listed, provided the pH is maintained within the recommended range and non-ionic thickeners are used with AcnePLEX™.

Always perform stability testing on your final formulation to confirm compatibility and product integrity.