Ingredient Compatibility for Cream Formulation

Question

Can the following ingredients be used together in a cream formulation? [url=http://www.myskinrecipes.com/shop/%E0%B8%99%E0%B9%89%E0%B8%B3%E0%B8%A1%E0%B8%B1%E0%B8%99%E0%B8%AA%E0%B8%81%E0%B8%B1%E0%B8%94%E0%B8%98%E0%B8%A3%E0%B8%A3%E0%B8%A1%E0%B8%8A%E0%B8%B2%E0%B8%95%E0%B8%B4/87-jojoba-oil-golden-%E0%B8%99%E0%B9%89%E0%B8%B3%E0%B8%A1%E0%B8%B1%E0%B8%99%E0%B9%82%E0%B8%88%E0%B9%82%E0%B8%88%E0%B9%89%E0%B8%9A%E0%B8%B2-%E0%B8%AD%E0%B8%AD%E0%B8%A2-%E0%B8%AA%E0%B8%81%E0%B8%B1%E0%B8%94%E0%B9%80%E0%B8%A2%E0%B9%87%E0%B8%99.html:zlxp3sfj]Simmondsia Chinensis[/url:zlxp3sfj] (Jojoba) Seed Oil, [url=http://www.myskinrecipes.com/shop/emulsifier/480-cetearyl-alcohol.html:zlxp3sfj]Cetearyl Alcohol[/url:zlxp3sfj], Stearic Acid, [url=https://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B9%88%E0%B8%A7%E0%B8%99%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%81%E0%B8%AD%E0%B8%9A%E0%B9%80%E0%B8%84%E0%B8%A3%E0%B8%B7%E0%B9%88%E0%B8%AD%E0%B8%87%E0%B8%AA%E0%B8%B3%E0%B8%AD%E0%B8%B2%E0%B8%87%E0%B8%84%E0%B9%8C/143-glycerin-%E0%B8%81%E0%B8%A5%E0%B8%B5%E0%B9%80%E0%B8%AA%E0%B8%AD%E0%B8%A3%E0%B8%B5%E0%B8%99.html:zlxp3sfj]Glycerin[/url:zlxp3sfj]e, [url=http://www.myskinrecipes.com/shop/%E0%B8%95%E0%B9%89%E0%B8%B2%E0%B8%99%E0%B8%AD%E0%B8%99%E0%B8%B8%E0%B8%A1%E0%B8%B9%E0%B8%A5%E0%B8%AD%E0%B8%B4%E0%B8%AA%E0%B8%A3%E0%B8%B0/65-vitamin-e-tocopheryl-acetate-%E0%B8%A7%E0%B8%B4%E0%B8%95%E0%B8%B2%E0%B8%A1%E0%B8%B4%E0%B8%99%E0%B8%AD%E0%B8%B5.html:zlxp3sfj]Tocopheryl Acetate[/url:zlxp3sfj], [url=https://www.myskinrecipes.com/shop/search?search_query=titanium+dioxide&orderby=position&orderway=desc:zlxp3sfj]Titanium Dioxide[/url:zlxp3sfj] and [url=http://www.myskinrecipes.com/shop/silica-lauroyl-lysine/518-silica-%E0%B8%94%E0%B8%B9%E0%B8%94%E0%B8%8B%E0%B8%B1%E0%B8%9A%E0%B8%84%E0%B8%A7%E0%B8%B2%E0%B8%A1%E0%B8%A1%E0%B8%B1%E0%B8%99%E0%B8%9C%E0%B8%B4%E0%B8%A7.html:zlxp3sfj]Silica[/url:zlxp3sfj] and [url=http://www.myskinrecipes.com/shop/236-silicone-oil-%E0%B9%84%E0%B8%A1%E0%B9%88%E0%B8%A3%E0%B8%B0%E0%B9%80%E0%B8%AB%E0%B8%A2:zlxp3sfj]Dimethicone[/url:zlxp3sfj], [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B8%AA%E0%B8%81%E0%B8%B1%E0%B8%94%E0%B8%9E%E0%B8%B7%E0%B8%8A%E0%B8%AA%E0%B8%A1%E0%B8%B8%E0%B8%99%E0%B9%84%E0%B8%9E%E0%B8%A3/76-aloe-vera-extract-%E0%B8%A7%E0%B9%88%E0%B8%B2%E0%B8%99%E0%B8%AB%E0%B8%B2%E0%B8%87%E0%B8%88%E0%B8%A3%E0%B8%B0%E0%B9%80%E0%B8%82%E0%B9%89%E0%B8%AA%E0%B8%81%E0%B8%B1%E0%B8%94.html:zlxp3sfj]Aloe Barbadensis Leaf Extract[/url:zlxp3sfj], [url=http://www.myskinrecipes.com/shop/%E0%B9%80%E0%B8%9B%E0%B9%81%E0%B8%97%E0%B9%84%E0%B8%97%E0%B8%94%E0%B9%8C%E0%B8%A5%E0%B8%94%E0%B8%A3%E0%B8%B4%E0%B9%89%E0%B8%A7%E0%B8%A3%E0%B8%AD%E0%B8%A2/762-madecassoside-centella-asiatica-extract.html:zlxp3sfj]Centella Asiatica[/url:zlxp3sfj] Leaf Extract, Oryza Sativa Seed Extract, [url=http://www.myskinrecipes.com/shop/%E0%B8%95%E0%B9%89%E0%B8%B2%E0%B8%99%E0%B8%AD%E0%B8%99%E0%B8%B8%E0%B8%A1%E0%B8%B9%E0%B8%A5%E0%B8%AD%E0%B8%B4%E0%B8%AA%E0%B8%A3%E0%B8%B0/65-vitamin-e-tocopheryl-acetate-%E0%B8%A7%E0%B8%B4%E0%B8%95%E0%B8%B2%E0%B8%A1%E0%B8%B4%E0%B8%99%E0%B8%AD%E0%B8%B5.html:zlxp3sfj]Tocopheryl Acetate[/url:zlxp3sfj], [url=https://www.myskinrecipes.com/shop/emulsifier/7446-aristoflex-avc-ammonium-acryloyldimethyltaurate-vp-copolymer.html:zlxp3sfj]Ammonium Acryloyldimethyltaurate/VP Copolymer[/url:zlxp3sfj], [url=http://www.myskinrecipes.com/shop/%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B8%81%E0%B8%B1%E0%B8%99%E0%B9%80%E0%B8%AA%E0%B8%B5%E0%B8%A2/155-phenoxyethanol-%E0%B8%AA%E0%B8%B2%E0%B8%A3%E0%B8%81%E0%B8%B1%E0%B8%99%E0%B9%80%E0%B8%AA%E0%B8%B5%E0%B8%A2-%E0%B9%84%E0%B8%A1%E0%B9%88%E0%B8%A1%E0%B8%B5paraben.html:zlxp3sfj]Phenoxyethanol[/url:zlxp3sfj] (Grade: Extra Pure), Botanical Extract Complex B, [url=http://www.myskinrecipes.com/shop/%E0%B8%A1%E0%B8%AD%E0%B8%A2%E0%B8%8B%E0%B9%8C%E0%B9%80%E0%B8%88%E0%B8%AD%E0%B8%A3%E0%B9%8C/105-hyaluronic-acid-nano-low-molecule.html:zlxp3sfj]Sodium Hyaluronate[/url:zlxp3sfj].

MySkinRecipes Expert · Accepted Answer

Ingredient Compatibility for Cream Formulation

The ingredients you listed are generally compatible for use together in a cream formulation. Here's a breakdown of the ingredient types and considerations:

Oil Phase Ingredients: Jojoba Oil, Cetearyl Alcohol, Stearic Acid, Tocopheryl Acetate (Vitamin E), Dimethicone, and Oryza Sativa Seed Extract (Oryzanol) are typically incorporated into the oil phase of an emulsion. Cetearyl Alcohol and Stearic Acid also function as thickeners and emulsifiers.
Water Phase Ingredients: Glycerin, Aloe Barbadensis Leaf Extract (Aloe Vera Extract), Centella Asiatica Leaf Extract, Ammonium Acryloyldimethyltaurate/VP Copolymer (Aristoflex AVC), Phenoxyethanol, and Sodium Hyaluronate are usually part of the water phase.
Powder Ingredients: Titanium Dioxide and Silica need to be properly dispersed, often in the oil or silicone phase for Titanium Dioxide (as indicated by the Dimethicone/Silica treated type) and potentially in the water phase for Silica (as an anti-caking agent).

Compatibility Considerations:

Emulsification: The combination of fatty alcohols (Cetearyl Alcohol), fatty acids (Stearic Acid), and a polymer emulsifier (Aristoflex AVC) should allow for the creation of a stable emulsion (cream). You will need to follow standard hot or cold process emulsification techniques depending on your chosen method and other ingredients.
pH Sensitivity: Centella Asiatica Extract and Oryzanol have optimal pH ranges (4-6.5). Ensure your final formulation's pH falls within a suitable range for all ingredients to maintain their efficacy and stability. Phenoxyethanol is stable over a wide pH range (2-9).
Electrolytes: Aloe Vera Extract is an electrolyte, which can sometimes affect the viscosity of formulations thickened with certain polymers like Aristoflex AVC. This interaction should be tested during your formulation process.
Dispersion: Ensure Titanium Dioxide and Silica powders are well dispersed in their respective phases before combining to avoid clumping and ensure smooth texture and even distribution.
Botanical Extract Complex B: The compatibility of this specific complex depends on its individual components, which are not detailed. Generally, botanical extracts are compatible, but it's always wise to check for any known incompatibilities if the components are known.

In summary, the ingredients form a logical basis for a cream formulation containing emollients, humectants, thickeners, emulsifiers, antioxidants, extracts, and a preservative. With proper formulation techniques and consideration of pH and dispersion, these ingredients can be used together effectively.