LHA Concentration in L'Oreal Studies and Melasma Treatment Efficacy
Question
I saw a L'Oreal brochure mentioning a study using `Capryloyl Salicylic Acid (LHA)`. Is it true that the study involved starting with `5% LHA` and increasing the concentration to `10%` at week 5? Also, is `Capryloyl Salicylic Acid (LHA)` effective for treating melasma, especially compared to `Glycolic Acid`? What are the common applications for `Capryloyl Salicylic Acid (LHA)`?
Answer
LHA Concentrations in L'Oreal Studies and Use for Melasma
Regarding your question about the L'Oreal brochure and the concentrations of Active LHA, based on the information available:
- The reply from cosmeceutical7 indicates that L'Oreal does use very high concentrations of actives like Glycolic Acid (20-50%) in their experimental trials, although these levels are not typically found in their final products. The reply also mentions LHA 5% (=Liquid LHA 50%) as a high concentration that requires caution.
- However, the provided information does not explicitly confirm that the specific L'Oreal study you saw in the brochure started with 5% LHA and increased to 10% at week 5. While L'Oreal conducts trials with LHA, the exact concentrations and timeline from that particular brochure cannot be verified from the available data.
- It is important to heed the caution mentioned about using high concentrations of AHA/BHA/LHA; proper knowledge is essential.
Concerning the use of LHA for treating melasma:
- The reply states that Glycolic Acid is known for treating melasma.
- However, the effectiveness of LHA for melasma is mentioned as being less established because it is newer and there are fewer study results available.
- The product description for Capryloyl Salicylic Acid (LHA) lists its uses primarily for wrinkle products, exfoliating products, and acne products. It does not specifically mention melasma treatment as a primary indication.
Therefore, while LHA is used in cosmetic products and L'Oreal conducts trials with it, the specific concentrations in your brochure study are not confirmed by the available text, and LHA's efficacy for melasma is not as well-established as that of Glycolic Acid, according to the provided information. The primary uses listed for Capryloyl Salicylic Acid (LHA) are exfoliation, wrinkles, and acne.