Lotion Formulation with Vitamin C and Whitening Agents: Effectiveness, Safety, and Mixing

Subject: Lotion Formulation with Vitamin C

Hello,

Regarding your questions about making a body lotion with Vitamin C:

1. Suitable Vitamin C Types: For a water-based lotion, it's recommended to use stable Vitamin C derivatives that can be mixed in water without degrading. The recommended options are Ethyl Ascorbic acid, Perfect-C, or Ascorbyl Glucoside (note that Ascorbyl Glucoside requires pH adjustment).
2. Creating the Cream Base: To ensure the lotion has a proper texture and isn't too liquid, you need to use an emulsifier (สารสร้างเนื้อครีม) and ingredients that contribute to the cream's feel, such as oils and silicones. The sample formula uses Satin Cream Maker as the emulsifier, along with Fractionated Coconut Oil and Dimethicone.
3. Ingredient Compatibility: Not all ingredients are compatible with Vitamin C. Specifically, Vitamin B3 (Niacinamide, like Safe-B3) can cause issues when mixed with certain forms of Vitamin C. However, fragrance and other whitening agents like Tranexamic Acid (Trans-White™), MSH White Absorb™, and WhiteCumin™ 2x are compatible.
4. Whitening Effectiveness (Tranexamic Acid vs MSH White Absorb™): The effectiveness between Tranexamic Acid (Trans-White™) and MSH White Absorb™ can vary depending on individual skin types.
5. Irritation Reducers: Adding irritation-reducing ingredients is generally not necessary when using the main ingredients at recommended concentrations, unless your skin is already prone to irritation. However, you can include them if desired, as in your proposed formula with Bisabolol.
6. Proposed Formula and Mixing Steps: Your proposed formula, which adds Bisabolol and either Tranexamic Acid (Trans-White™) or MSH White Absorb™ to the base formula, is mixable.
   • Proposed Formula Example (using Ethyl Ascorbic acid and Tranexamic Acid):
     • Satin Cream Maker 1% (Emulsifier)
     • Phenoxyethanol SA 1% (Preservative)
     • Fractionated Coconut Oil 5% (Oil phase)
     • Dimethicone 5% (Silicone)
     • MOIST24 8% (Humectant)
     • Bisabolol (German Chamomile Extract) (Irritation Reducer) - adjust percentage as per product instructions
     • Ethyl Ascorbic acid 5% (or Perfect-C 5%, or Ascorbyl Glucoside 5%) (Vitamin C)
     • Tranexamic Acid (Trans-White™) 3% (or MSH White Absorb™ 6%) (Whitening Agent)
     • Water: Remaining percentage to reach 100%
   • Mixing Steps:
     • Mix the water phase ingredients together.
     • Add Satin Cream Maker to the water phase and stir/blend until a cloudy gel forms.
     • Mix the oil phase ingredients (Fractionated Coconut Oil, Dimethicone, etc.) together.
     • Slowly add the oil phase mixture into the cloudy gel while stirring or blending until a cream texture is achieved.
7. Safety of Tranexamic Acid and MSH White Absorb™: When used at levels within the manufacturer's or regulatory limits, both Tranexamic Acid (Trans-White™) and MSH White Absorb™ are considered safe for long-term use and do not have inherent side effects. However, as with any cosmetic ingredient, individual allergic reactions are possible. If you experience any adverse reaction, discontinue use.

Hope this helps with your lotion making!