Mechanism of Action and Synergy of Acne Treatment Ingredients

Asked by: glutacareshop On: October 01, 2017 Product Type: Cosmetics

Question

Could you please explain the mechanism of action for Encapsulated Salicylic Acid, Nano Silver, and Licorice Extract in treating acne, particularly clogged pores? I'm also curious if Encapsulated Salicylic Acid helps 'push out' clogs similar to Vitamin A. Furthermore, how do Nano Silver and Licorice Extract work, and do their anti-inflammatory properties interfere with the function of Encapsulated Salicylic Acid when used together in a formulation?

Answer

Hello!

It sounds like you have questions about how Encapsulated Salicylic Acid, Nano Silver, and Licorice Extract work together to treat acne, especially clogged pores, and you're concerned that anti-inflammatory ingredients might interfere with Salicylic Acid's action. I can explain the mechanism of each ingredient based on the information provided:

  • Encapsulated Salicylic Acid (BHA): This ingredient primarily works by dissolving clogged pores (comedones). It helps exfoliate dead skin cells and debris that block pores, allowing the clogs to loosen and be removed. The encapsulated form provides a gentler, timed release. Salicylic Acid also has antibacterial properties, which helps reduce inflammation caused by bacteria.

    • Clarification: The action of pushing clogs or pus to the skin surface is typically associated with Vitamin A (Retinoids), not Salicylic Acid. Salicylic Acid focuses on dissolving the blockage within the pore.
  • Nano Silver: Nano-sized silver has potent antimicrobial properties. It effectively eliminates bacteria like P. acnes, a major contributor to inflammatory acne. By reducing bacterial load, it helps reduce inflammation.

  • Licorice Extract (specifically Licochalcone A): Licorice extract is an excellent anti-inflammatory agent. It works through a different mechanism than Nano Silver, by inhibiting inflammatory pathways in the skin, such as inhibiting Pro-inflammatory Cytokine Inhibitors. This helps reduce redness and irritation associated with acne.

How they work together:

These three ingredients have different mechanisms but complement each other in treating acne:

  • Encapsulated Salicylic Acid addresses the root cause of clogged pores by dissolving the blockage.
  • Nano Silver and Licorice Extract help reduce and prevent inflammation that might occur. Nano Silver targets bacteria, while Licorice Extract targets the skin's inflammatory response.

Therefore, using these three ingredients together in a formula does not counteract Salicylic Acid's function. Instead, they work synergistically to provide comprehensive acne treatment by dissolving clogs, killing bacteria, and reducing skin inflammation, leading to faster healing and reducing the chance of clogged pores developing into inflamed acne.