Mechanism of Action for Warming Ingredients

Ingredients like Vanillyl Butyl Ether, often used to create a warming sensation in cosmetic formulations, work by interacting with specific receptors in the skin.

The primary mechanism involves the activation of the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor. This receptor is a type of ion channel found in nerve cells in the skin. It is naturally activated by stimuli such as heat (temperatures above 43°C) and certain chemical compounds, including capsaicin (the active component in chili peppers).

When Vanillyl Butyl Ether is applied to the skin, it binds to and activates the TRPV1 receptors. This activation sends a signal through the nervous system to the brain, which is interpreted as a sensation of warmth or heat. This feeling occurs without causing an actual increase in the skin's temperature.

Regarding specific documentation for "Chili Hot" (Vanillyl Butyl Ether), I was unable to locate detailed technical documents within the available database.