Melasma Serum Formulation with Silky Serum Base: Percentages and Application Time

Hello!

Regarding your questions about the serum formulation:

1. Mixing Procedure: Your proposed method of dissolving water-soluble ingredients first and then gradually adding them to the Silky Serum Base while mixing is a common and generally correct approach for creating this type of serum. However, as previously mentioned by the staff, it is crucial to follow the specific mixing instructions provided for the Silky Serum Base product to ensure proper emulsification and stability.

2. Silky Serum Base Percentage: After removing the 3% Oxyresveratrol, the correct percentage for the Silky Serum Base to maintain a total of 100% in your formula should be 33%, not 34%. The adjusted formula would be:

   • Silky Serum Base: 33%
   • Water: 50%
   • Alpha-Arbutin: 2%
   • Vitamin B3: 4%
   • N-Acetyl Glucosamine: 4%
   • Azelaic Acid: 5%
   • Tranexamic Acid: 2%
   • Total: 100%

3. Application Time: Given the combination of active ingredients aimed at treating melasma, including Azelaic Acid which can increase sun sensitivity, it is generally recommended to apply this serum at night. This helps to maximize the effectiveness of the ingredients while minimizing the risk of sun-induced irritation or worsening of pigmentation. Remember that consistent daily use of a high-SPF sunscreen is absolutely essential when treating melasma, regardless of when you apply the serum.

Thank you!