Mixing L-Tyrosine (Acetyl-Tyrosine) and Copper Peptide (GHK-Cu) for Derma Rolling

To mix L-Tyrosine (specifically Acetyl-Tyrosine, such as Wrinkle-Fill™) and Copper Peptide (GHK-Cu) for use with a derma roller, you will need to create a serum or gel base.

Here's a general guide on how to mix them in a 100ml formula:

1. Prepare your base: Start with approximately 95-98 ml of your chosen serum or gel base. Ensure the base is compatible with active ingredients and can accommodate pH adjustment.

2. Add Acetyl-Tyrosine: Acetyl-Tyrosine (like Wrinkle-Fill™) is typically a powder. Add 1-2 grams of Acetyl-Tyrosine to the water phase of your base formula and ensure it is fully dissolved.

3. Add Copper Peptide (GHK-Cu): Copper Peptide should be added in the final step, once the temperature of your formula is below 40°C. The amount depends on the form you are using:

   • If using Copper Peptide (GHK-Cu, 1000ppm Solution): Add 1-3 ml.
   • If using Copper Peptide (GHK-Cu Powder): Add 0.01-1 gram.
   • If using Copper Tripeptide 10x (GHK-Cu, 10000ppm Solution): Add 1-3 ml.

4. Adjust pH: This is a critical step. Acetyl-Tyrosine is acidic, while Copper Peptide requires a pH range of 4.5-7.4 for stability and effectiveness. After adding both ingredients, check the pH of your final mixture. If it is too low (below 4.5), you will need to carefully add a pH adjuster (such as a dilute solution of sodium hydroxide) drop by drop until the pH is within the optimal range of 4.5-7.4.

5. Add Preservative: Since this is a water-based product, adding a suitable preservative is essential to prevent bacterial and fungal growth, especially when used with a derma roller which breaks the skin barrier.

6. Final Mixing: Mix thoroughly to ensure all ingredients are evenly distributed.

Both Acetyl-Tyrosine and Copper Peptide (GHK-Cu) are suitable for use with a derma roller and are known for their skin-renewing and anti-aging properties. Always perform a patch test before applying the final product to your face.