Answers to Your Formulation Questions

Here are the answers to your questions regarding mixing ingredients into your existing cosmetic products, based on the information provided:

1. Mixing Apple Stem Cell into Cream with DMAE and Alpha Lipoic Acid

Yes, you can mix Apple Stem Cell Extract into your face cream that contains DMAE and Alpha Lipoic Acid, provided the cream's pH is suitable for Apple Stem Cell (ideally above 5.5). Apple Stem Cell Extract is a powder that dissolves in water. It is recommended to mix it into the final product at a temperature below 40°C.

Regarding the quantity, you don't need to aim for a total of exactly 100g. You should calculate the amount of Apple Stem Cell based on the percentage you want (5%) and the amount of cream you have. For example, if you have 50g of cream, you would add 5% of 50g, which is 2.5g of Apple Stem Cell Extract.

2. Mixing DMAE, Pepha Tight, and Apple Stem Cell into Hada Labo (Blue Bottle) with Arbutin

While it's possible to mix ingredients into the Hada Labo lotion, adding DMAE (especially the Bitartrate form) is not recommended because it is highly acidic and would significantly lower the pH of the lotion, potentially causing instability or requiring complex pH adjustment. Apple Stem Cell also prefers a pH above 5.5.

Instead, for enhancing the Hada Labo lotion, it is recommended to add:

• Niacinamide (Vitamin B3) 4%
• Apple Stem Cell Extract 5%
• Peptides for wrinkles, such as Acetyl Hexapeptide-8 (Argireline) 3-5% or Acetyl Octapeptide-3 (SNAP-8) 5%
• Optionally, Acetyl Glucosamine (GlucoBright™) 4% for additional whitening benefits.

Many of these active ingredients, including Apple Stem Cell Extract, Acetyl Hexapeptide-8, and Acetyl Octapeptide-3, benefit from being stored in the refrigerator for long-term preservation after mixing.

3. Mixing Arbutin and Glucosamine into Vaseline Healthy White Lotion with B3

Yes, you can mix Alpha Arbutin 2% and Acetyl Glucosamine (GlucoBright™) 4% into your Vaseline Healthy White lotion (which contains Niacinamide/B3) to focus on whitening. However, since both Alpha Arbutin and Acetyl Glucosamine are powders, you should first dissolve them completely in a small amount of water before mixing them into the lotion. This ensures they are properly dispersed and effective.

Similar to question 1, you do not need to end up with exactly 100g total. Calculate the amount of Alpha Arbutin and Acetyl Glucosamine based on the percentages and the amount of lotion you are using. For example, if you have 50g of lotion, you would add 2% of 50g (1g) of Alpha Arbutin and 4% of 50g (2g) of Acetyl Glucosamine, dissolved in a small amount of water.

4. Whitening Difference with or without MAP Vitamin C

In the context of mixing into your existing lotion with Niacinamide and adding Alpha Arbutin and Acetyl Glucosamine, adding Magnesium Ascorbyl Phosphate (MAP) Vitamin C is not recommended. MAP is alkaline and requires a high pH (7-9) for stability, whereas Alpha Arbutin, Niacinamide, and Acetyl Glucosamine are more stable and effective at a lower pH (generally between 3.5-7). Adding MAP would disrupt the pH balance needed for the other whitening ingredients to work optimally and remain stable, making the formulation process complicated. The combination of Alpha Arbutin, Niacinamide (already in the lotion), and Acetyl Glucosamine is already an effective approach for skin brightening without the pH challenges introduced by MAP.