Mixing Ascorbyl Glucoside (AA2G) with L-Arginine for Stabilization
Question
Based on the information provided on the Ascorbyl Glucoside product page stating:
If you are unable to prepare Citrate Buffer as recommended above, please use L-Arginine at a ratio of 1:2 (L-Arginine 1 part per AA2G 2 parts). Mix well and dissolve in water together. L-Arginine can help control the pH to prevent AA2G from degrading.
Regarding the statement "ratio of 1:2 = L-Arginine 1 part per AA2G 2 parts":
- If the formula contains Ascorbyl Glucoside 10%, does that mean I need to add L-Arginine 5%?
- Following up from question (1), the L-Arginine product page states a usage rate of 0.1-1%. I am currently having trouble with formulating 10% Ascorbyl Glucoside using L-Arginine because of this. Can L-Arginine be used at a concentration higher than 1%?
Thank you.
Answer
Mixing Ascorbyl Glucoside (AA2G) with L-Arginine
Regarding your questions about mixing Ascorbyl Glucoside (AA2G) and L-Arginine based on the information provided on the product pages:
Ratio Calculation: Yes, if your formula contains 10% Ascorbyl Glucoside and you are following the specific instruction to use L-Arginine at a 1:2 ratio (L-Arginine : AA2G) for stabilization, then you would indeed need to use 5% L-Arginine.
Usage Rate Conflict: The general recommended usage rate for L-Arginine (0.1-1%) is typically for its other cosmetic benefits. However, the instruction to use L-Arginine at a 1:2 ratio with Ascorbyl Glucoside is a specific recommendation for buffering and stabilizing the AA2G, which is highly acidic. When used for this specific pH adjustment purpose, a higher concentration of L-Arginine, such as the calculated 5% for 10% AA2G, is necessary and acceptable to achieve the required pH range (6.5-6.8) for AA2G stability. Therefore, for the purpose of stabilizing 10% Ascorbyl Glucoside, using 5% L-Arginine according to the 1:2 ratio is correct, overriding the general usage rate guideline for other applications.
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