Mixing Multiple Peptide and Ferment Ingredients

Yes, you can generally mix Galactomyces Ferment Filtrate, Repair Activator (Bifida Ferment Lysate), Pep-Coll (Palmitoyl Tripeptide-5), Argireline (Acetyl Hexapeptide-8), and Copper Peptide (GHK-Cu) together in one bottle to create a combined serum. These ingredients are water-soluble and are typically added in the final phase of a formulation at temperatures below 40°C.

Compatibility and pH

The compatibility of these ingredients is good, especially within a specific pH range. Based on the recommended pH ranges for each ingredient:

• Galactomyces Ferment Filtrate: pH 4-7
• Repair Activator: pH 4-5.5
• Pep-Coll: pH not specified, but generally compatible with peptides
• Argireline: pH 3.5-6.5
• Copper Peptide: pH 4.5-7.4

The optimal pH range for a mixture containing all these ingredients would be approximately pH 4.5 to 5.5 to ensure the stability and efficacy of each component, particularly Repair Activator and Copper Peptide.

Preservative Requirement

Since your formulation will be water-based (using Galactomyces as the base) and you are mixing multiple ingredients, adding a broad-spectrum preservative is highly recommended. While some of the ingredients like Argireline, Repair Activator, and Galactomyces (ID 357) contain some form of preservative or stabilizing agent, the total concentration may not be sufficient to protect the entire 160ml volume from microbial growth over time, especially considering the varying shelf lives of the individual components.

Adding a suitable preservative will help maintain the safety and stability of the final product throughout its usage period.

Shelf Life and Storage

When mixing ingredients with different shelf lives, the shelf life of the final product is typically limited by the ingredient with the shortest expiry date. Given that some components have a 60-day shelf life, it would be prudent to aim to use the mixed product within 2-3 months and store it properly. Refrigeration (4-8°C) is recommended for storing the individual ingredients and the final mixture to help maintain their potency and extend their usability within the stated shelf lives.

In summary, mixing these ingredients is feasible, but pay close attention to the final pH and definitely include a broad-spectrum preservative for safety and stability. Store the final product in the refrigerator.