Mixing Instructions for Cream Formulation with Multiple Actives

Asked by: rika_run On: March 19, 2016 Product Type: Cosmetics

Question

I have a cream formulation with the following ingredients, categorized into water and oil phases:

Water Phase:

    1. Distilled Water
    1. Azelaic Acid
    1. Tranexamic Acid
    1. Satin Mousse
    1. DMAE
    1. Disodium EDTA
    1. N-Acetyl-D glucosamine
    1. Niacinamide
    1. Phenoxyethanol
    1. Pro Polymer

Oil Phase:

    1. LipidSoft Lite
    1. Activated Resorcinol

Could you please provide detailed mixing instructions for this formula to ensure it forms a stable cream texture and avoids phase separation over time?

Answer

Mixing Instructions for Revised Cream Formula (Based on Your Numbering)

Based on your re-numbered list, here are the mixing steps for the cream formulation:

  1. Water Phase (Part 1): Combine ingredients #1 (Distilled Water), #4 (Tranexamic Acid), #7 (Disodium EDTA), #9 (N-Acetyl-D glucosamine), #10 (Niacinamide), and #11 (Phenoxyethanol). Mix until well combined.
  2. Thickening: Add ingredient #12 (Pro Polymer) to the mixture from Step 1. Mix or stir until a thick gel consistency is achieved.
  3. Adding Actives: Gradually add ingredient #2 (Azelaic Acid) and #6 (DMAE) to the gel from Step 2, mixing thoroughly after each small addition. The gel may thin out.
  4. Adjusting Consistency: If the gel becomes too thin, add ingredient #5 (Satin Mousse) to thicken it. If adding all of #5 is still not enough to maintain a suitable gel consistency while adding #2 and #6, add more of #12 (Pro Polymer) until the desired consistency is reached and all of #2 and #6 are incorporated.
  5. Oil Phase: In a separate container, combine ingredients #3 (LipidSoft Lite) and #8 (Activated Resorcinol). Mix until the mixture is clear.
  6. Emulsification: Gradually add the oil phase mixture from Step 5 to the water phase gel from Step 4. Mix continuously until a homogeneous cream texture is formed.