Mixing Wrinkle-Fill (L-Tyrosine) with other products and simple formula pH

Hello,

Regarding your questions and the staff's previous response, here is a summary and additional information:

1. Mixing Wrinkle-Fill (L-Tyrosine) with Galactomyces Ferment Filtrate (Pitera), existing lotions (like Hada Labo), or Stabilized Vitamin C (Natural-C Glycol™) Serum:

   • As the staff mentioned, yes, you can mix them.
   • The most important condition is that you must check the pH of the final mixed product to ensure it is within the optimal range for Wrinkle-Fill, which is pH 3-6.5.
   • L-Tyrosine (Wrinkle-Fill) is most stable and effective in reducing wrinkles within this pH range. Mixing it with products outside this range might reduce its efficacy or stability.

2. Simple Usage Methods or Simple Formula:

   • The simplest method, if you don't want to create a new formula at all, is to mix Wrinkle-Fill 2% directly with your existing facial lotion (like Hada Labo or other water-based lotions) in a small amount for each use (e.g., mix on your palm). However, you must ensure that the lotion has a pH within or close to the 3-6.5 range. (Most finished lotions typically have a pH around 5-6, which might be usable, but it's best to check to be sure).
   • Your proposed simple formula (Wrinkle-Fill 2%, Preservative 1%, rest water): This is a viable basic formula.
     • 2% Wrinkle-Fill is an appropriate concentration for an active ingredient.
     • 1% preservative (depending on the type of preservative) is necessary for water-based formulas to prevent microbial growth.
     • Crucially, for this formula, you must adjust the pH of the final mixture to be within the 3-6.5 range for Wrinkle-Fill to be fully effective and stable. You might need to use a mild acid or base to adjust the pH.
     • Making this formula separately and then applying another lotion afterward is a correct usage method.

In Summary: Whether you mix Wrinkle-Fill directly with other products or make a simple water-based formula separately, the key is to control the pH of the final product to be within the 3-6.5 range to get the maximum benefit from Wrinkle-Fill.