Mouth Spray Formulation: Base, Preservatives, and Active Ingredients

Mouth Spray Formulation: Basic Components and Active Ingredients

For creating a safe and effective mouth spray, you can consider the following key components:

1. Base

The base for a mouth spray is typically a water-based formula. It may include humectants like Glycerin to provide a comfortable mouthfeel and potentially a small amount of alcohol or a solubilizer to help dissolve water-insoluble ingredients such as essential oils.

• Enzyme Mouthwash (e.q. Propolinse, 1:4 Concentrate) (Product ID 10984) is a concentrated mouthwash base that can be adapted. It must be diluted with water at a 1:4 ratio before use, and other ingredients like sweeteners or cooling agents can be added.

2. Preservatives

Preservatives are crucial to prevent microbial contamination and extend the product's shelf life. For oral products, it's important to choose preservatives that are safe and approved for oral use.

• Preserve-BSB™ (eq. Optiphen BSB-W) (Product ID 127176) is a preservative containing Benzyl Alcohol, Sodium Benzoate, and Potassium Sorbate, which are common ingredients in oral care products. It offers broad-spectrum efficacy against bacteria, yeast, and mold and is suitable for formulas with a pH of 2-5.5.
• NaturePreserve™ LB2 (Product ID 127320) is a natural-origin preservative with high efficacy against bacteria and fungi in low pH formulas (2.0-6.5). It contains Dehydroacetic Acid, Benzoic Acid, and Benzyl Alcohol.

3. Active Ingredients and Sensory Agents

Active ingredients help add special properties to the mouth spray, such as helping to reduce bad breath, providing a cooling sensation, or having properties that inhibit oral bacteria.

• Four-EO™ (Product ID 1237) is a blend of four essential oil extracts: Thymol, Eucalyptol, Menthol, and Menthyl Salicylate. It helps inhibit and control oral bacteria causing bad breath and provides a cool, fresh feeling. Poloxamer 407 can be used as a solubilizer to incorporate it into a water base.
• CleanTea™ Liquid (Green Tea Extract Deodorizer) (Product ID 31621) is a green tea extract effective in suppressing various odors, including bad breath. It can be used in oral hygiene products.
• Water-Cool™ (Water-Soluble Cooling Agent) (Product ID 31989) provides a cooling sensation and is directly water-soluble, making it suitable for water-based spray formulas for a fresh feeling in the mouth.
• CoCool™ (Menthol+Menthyl Lactate, e.q.Frescolat Plus) (Product ID 31510) provides a cooling sensation and is soluble in oil or Glycol. It gives a cool feeling upon contact.
• OralCap™ Peppermint (Product ID 125343) is an encapsulated form of Peppermint Oil in small edible softgels. It can be used to provide peppermint flavor and sensation.

Additional Recommendations:

• If you wish to use other essential oils as active ingredients, ensure they are safe for oral use (Food Grade or Oral Care Grade). You will need an appropriate solubilizer, such as Poloxamer 407, to help the essential oil disperse well in the water base without separating.
• Compatibility testing of ingredients and preservative efficacy testing (Challenge Test) on the final formula are recommended before commercial production.